From independent modules to molten globules: observations on the nature of protein folding intermediates.

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

INTERMEDIATES IN THE FOLDING REACTIONS OF SMALL PROTEINS

1990 • 1,133 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Structural Characterization of a Partly Folded Apomyoglobin Intermediate

1990 • 708 citations

Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium.

1988 • 706 citations

Evidence for a molten globule state as a general intermediate in protein folding

1990 • 677 citations

Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin

1985 • 622 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig .alpha.-lactalbumin

1989 • 473 citations

Structural description of acid-denatured cytochrome c by hydrogen exchange and 2D NMR

1990 • 306 citations

Thermodynamic study of the apomyoglobin structure

1988 • 299 citations

Early hydrogen-bonding events in the folding reaction of ubiquitin.

1992 • 220 citations

The folding of an enzyme

1992 • 216 citations

Early folding intermediate of ribonuclease A.

1990 • 180 citations

The folding of an enzyme

1992 • 97 citations

Guanidine hydrochloride stabilization of a partially unfolded intermediate during the reversible denaturation of protein disulfide isomerase.

1993 • 73 citations

Simulations of the folding pathway of triose phosphate isomerase-type alpha/beta barrel proteins.

1992 • 47 citations

Characterizing protein folding intermediates

1991 • 42 citations

[Self-organization of the myoglobin molecule].

1973 • 26 citations