Dopamine D4 receptor gene (DRD4) is associated with Novelty Seeking (NS) and substance abuse: the saga continues . . .

Sensation Seeking : Beyond the Optimal Level of Arousal

1979 • 2,591 citations

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking

1996 • 1,498 citations

Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking

1996 • 1,207 citations

A hypervariable segment in the human dopamine receptor D₄ (DRD4) gene

1993 • 536 citations

Studies of the 48 bp repeat polymorphism of theDRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse

1999 • 291 citations

D2 and D4 dopamine receptor polymorphisms and personality

1998 • 289 citations

The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking.

1996 • 233 citations

Association between tridimensional personality questionnaire (TPQ) traits and three functional polymorphisms: dopamine receptor D4 (DRD4), serotonin transporter promoter region (5-HTTLPR) and catechol O-methyltransferase (COMT)

2000 • 198 citations

D4 Dopamine-Receptor (DRD4) Alleles and Novelty Seeking in Substance-Dependent, Personality-Disorder, and Control Subjects

1997 • 191 citations

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects

1997 • 181 citations

Identification of a polymorphism in the promoter region of DRD4associated with the human novelty seeking personality trait

2000 • 171 citations

Dopamine D4 receptors and the risk of cigarette smoking in African-Americans and Caucasians.

1998 • 148 citations

Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene

1997 • 147 citations

Association between dopamine D4 receptor (D4DR) Exon III polymorphism and novelty seeking in Japanese subjects

1997 • 134 citations

Lack of evidence for allelic association between personality traits and the dopamine D4 receptor gene polymorphisms

1997 • 126 citations

Association between the dopamine D4 receptor (DRD4) exon III polymorphism and measures of Novelty Seeking in a German population

1999 • 124 citations

Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics

1997 • 121 citations

Association Between Novelty Seeking and the Type 4 Dopamine Receptor Gene in a Large Finnish Cohort Sample

1999 • 121 citations

No association between Novelty Seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging participants

1997 • 117 citations

Human novelty-seeking personality traits and dopamine D4 receptor polymorphisms: a twin and genetic association study.

1998 • 111 citations

Human novelty-seeking personality traits and dopamine D4 receptor polymorphisms: a twin and genetic association study

1998 • 94 citations

Pathological gambling and DNA polymorphic markers at MAO-A and MAO-B genes

2000 • 94 citations

Allelic variants of dopamine receptor D4 (DRD4) and serotonin receptor 5HT2c (HTR2c) and temperament factors: Replication tests

1999 • 88 citations

No Association Between Novelty Seeking and the Type 4 Dopamine Receptor Gene (DRD4) in Two New Zealand Samples

1998 • 88 citations

Association between novelty seeking and dopamine receptor D4 (DRD4) exon III polymorphism in Japanese subjects

1999 • 84 citations

Saga of an adventure gene: Novelty Seeking, substance abuse and the dopamine D4 receptor (D4DR) exon III repeat polymorphism

1997 • 83 citations

Association between alcoholism and the dopamine D4 receptor gene.

1996 • 78 citations

No Association Between Polymorphisms in the Human Dopamine D3 and D4 Receptors Genes and Alcoholism

1997 • 53 citations

DRD4 dopamine receptor genotype and CSF monoamine metabolites in Finnish alcoholics and controls

1995 • 52 citations

Lack of association between dopamine D4 receptor gene and personality traits

1998 • 49 citations

DRD4 exon III VNTR polymorphism—susceptibility factor for heroin dependence? Results of a case-control and a family-based association approach

2000 • 43 citations

Dopamine D4 receptor gene and personality dimensions in Brazilian male alcoholics

1999 • 40 citations

Tyrosine Hydroxylase and Dopamine D4 Receptor Allelic Distribution in Scandinavian Chronic Alcoholics

1997 • 40 citations

Rapid molecular haplotyping of the first exon of the human dopamine D4 receptor gene by heteroduplex analysis

1997 • 26 citations

Lack of association of the dopamine D4 receptor gene polymorphism with alcoholism in a Brazilian population

1999 • 26 citations

Mapping genes for personality: is the saga sagging?

1998 • 20 citations

Dopamine D4 receptor gene and severity of dependence

2000 • 15 citations

Association Study Between Genetic Polymorphisms in the 14–3‐3 η Chain and Dopamine D4 Receptor Genes and Alcoholism

2000 • 14 citations

No significant associations between two dopamine receptor polymorphisms and normal temperament

1998 • 5 citations