Release of cell surface‐associated basic fibroblast growth factor by glycosylphosphatidylinositol‐specific phospholipase C

Angiogenic Factors

1987 • 3,702 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Proteoglycans as modulators of growth factor activities

1991 • 1,338 citations

Recent developments in the cell biology of basic fibroblast growth factor.

1989 • 1,049 citations

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Structural and Functional Roles of Glycosyl-Phosphatidylinositol in Membranes

1988 • 963 citations

A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.

1988 • 892 citations

Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation.

1988 • 810 citations

Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth

1987 • 764 citations

High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells

1987 • 653 citations

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

1988 • 647 citations

Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules

1989 • 597 citations

Cell-Surface Glycosaminoglycans

1984 • 552 citations

Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity.

1990 • 545 citations

Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues.

1990 • 533 citations

Structure and function of heparan sulphate proteoglycans

1986 • 485 citations

The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction

1989 • 482 citations

Clonal growth of bovine vascular endothelial cells: fibroblast growth factor as a survival agent.

1976 • 423 citations

Basic fibroblast growth factor enters the nucleolus and stimulates the transcription of ribosomal genes in ABAE cells undergoing G0----G1 transition.

1987 • 422 citations

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

1987 • 416 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells.

1985 • 352 citations

Stimulation of corneal endothelial cell proliferation in vitro by fibroblast and epidermal growth factors

1977 • 335 citations

Translocation of bFGF to the nucleus is G1 phase cell cycle specific in bovine aortic endothelial cells.

1990 • 324 citations

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.

1990 • 292 citations

A novel pathway for secretory proteins?

1990 • 292 citations

[7] Isolation and characterization of connective tissue polysaccharides

1972 • 280 citations

Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.

1990 • 274 citations

A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma.

1988 • 261 citations

Expression of basic fibroblast growth factor in normal human tissues.

1990 • 258 citations

Involvement of phosphatidylinositol and insulin in the coordinate regulation of proteoheparan sulfate metabolism and hepatocyte growth.

1987 • 237 citations

Role of extracellular matrix in the action of basic fibroblast growth factor: Matrix as a source of growth factor for long‐term stimulation of plasminogen activator production and DNA synthesis

1989 • 227 citations

Transport of heparan sulfate into the nuclei of hepatocytes.

1986 • 190 citations

Basic fibroblast growth factor is an extracellular matrix component required for supporting the proliferation of vascular endothelial cells and the differentiation of PC12 cells.

1989 • 190 citations

Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells.

1991 • 186 citations

Cell surface proteoglycan expression correlates with epithelial-mesenchymal interaction during tooth morphogenesis

1988 • 181 citations

Isolation, characterization, and localization of heparin-binding growth factors in the heart.

1990 • 175 citations

Heparin sequences in the heparan sulfate chains of an endothelial cell proteoglycan.

1987 • 161 citations

Cell-specific heterogeneity in sensitivity of phosphatidylinositol-anchored membrane antigens to release by phospholipase C

1988 • 157 citations

Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan.

1991 • 145 citations

Purification of a phosphatidylinositol-glycan-specific phospholipase C from liver plasma membranes: a possible target of insulin action.

1987 • 142 citations

Purification of a Glycosyl-Phosphatidylinositol-specific Phospholipase D from Human Plasma

1989 • 135 citations

Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth.

1988 • 134 citations

Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin.

1990 • 123 citations

Regulation of Vascular Smooth Muscle Cell Growth by Heparin and Heparan Sulfates

1987 • 106 citations

Are factors originating from serum, plasma, or cultured cells involved in the growth‐promoting effect of the extracellular matrix produced by cultured bovine corneal endothelial cells?

1983 • 105 citations

Basic fibroblast growth factor accumulates in the nuclei of various bFGF-producing cell types

1990 • 98 citations

Conversion of human placental alkaline phosphatase from a high Mr form to a low Mr form during butanol extraction. An investigation of the role of endogenous phosphoinositide-specific phospholipases

1986 • 93 citations

Conditions required for expression of membrane IL 1 on B cells.

1985 • 84 citations

Dual Effect of Normal and Stimulated Macrophages and Their Conditioned Media on Target Cell Proliferation

1979 • 68 citations

Membrane anchoring of heparan sulfate proteoglycans by phosphatidylinositol and kinetics of synthesis of peripheral and detergent-solubilized proteoglycans in Schwann cells.

1989 • 64 citations

Regulation of chondrogenesis by heparan sulfate and structurally related glycosaminoglycans

1987 • 62 citations

Isolation and characterization of a phosphatidylinositol‐glycan‐anchor‐specific phospholipase D from bovine brain

1990 • 58 citations

Two Forms of Plasma Membrane-intercalated Heparan Sulfate Proteoglycan in Rat Ovarian Granulosa Cells

1989 • 52 citations

Phosphatidylinositol-specific phospholipase C releases lipoprotein lipase from the heparin releasable pool in rat heart cell cultures

1989 • 34 citations

Antibodies against basic fibroblast growth factor inhibit the autocrine growth of pulmonary artery endothelial cells

1988 • 32 citations

Involvement of cell surface phosphatidylinositol-anchored glycoproteins in cell-cell adhesion of chick embryo myoblasts.

1989 • 29 citations

Expression of a chronic granulomatous disease-like defect by fluoride- exhausted neutrophils

1982 • 23 citations

Glycosylphosphatidylinositol is involved in the membrane attachment of proteins in granules of chromaffin cells

1988 • 22 citations

Stimulation of paracrine and autocrine pathways of cell proliferation by platelet-derived growth factor.

1988 • 11 citations