Cooperative Regulation of CYP2C12 Gene Expression by STAT5 and Liver-specific Factors in Female Rats

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Evidence for an Endogenous Ultradian Rhythm Governing Growth Hormone Secretion in the Rat

1976 • 743 citations

Functional interactions between Stat5 and the glucocorticoid receptor

1996 • 681 citations

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

1990 • 615 citations

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

1989 • 545 citations

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.

1993 • 543 citations

Age- and Sex-Related Differences in Episodic Growth Hormone Secretion in the Rat*

1979 • 543 citations

Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

1994 • 542 citations

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

1991 • 517 citations

Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene.

1985 • 290 citations

Mechanism of signaling by growth hormone receptor

1996 • 264 citations

Intermittent Plasma Growth Hormone Triggers Tyrosine Phosphorylation and Nuclear Translocation of a Liver-Expressed, Stat 5-related DNA Binding Protein.

1995 • 242 citations

Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats

1983 • 233 citations

Growth Hormone Activation of Stat 1, Stat 3, and Stat 5 in Rat Liver

1996 • 225 citations

p300/CREB-Binding Protein Enhances the Prolactin-Mediated Transcriptional Induction through Direct Interaction with the Transactivation Domain of Stat5, but Does Not Participate in the Stat5-Mediated Suppression of the Glucocorticoid Response

1998 • 217 citations

Mediation of Growth Hormone-dependent Transcriptional Activation by Mammary Gland Factor/Stat 5

1995 • 169 citations

Characterization of Stat5a and Stat5b Homodimers and Heterodimers and Their Association with the Glucocortiocoid Receptor in Mammary Cells

1998 • 164 citations

Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds.

1993 • 154 citations

Distinctive Roles of STAT5a and STAT5b in Sexual Dimorphism of Hepatic P450 Gene Expression

1999 • 152 citations

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion.

1992 • 140 citations

Regulation of Signal Transducer and Activator of Transcription (STAT) 5b Activation by the Temporal Pattern of Growth Hormone Stimulation

1997 • 129 citations

Elf-1 and Stat5 Bind to a Critical Element in a New Enhancer of the Human Interleukin-2 Receptor α Gene

1996 • 117 citations

Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes.

1992 • 115 citations

In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.

1995 • 106 citations

Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats.

1984 • 105 citations

Expression of hepatocyte nuclear factor 6 in rat liver is sex-dependent and regulated by growth hormone

1997 • 104 citations

Phenobarbital Induction Mediated by a Distal CYP2B2 Sequence in Rat Liver Transiently Transfected in Situ

1996 • 101 citations

Effect of Growth Hormone and Ectopic Transplantation of Pituitary Gland on Sex-Specific Forms of Cytochrome P-450 and Testosterone and Drug Oxidations in Rat Liver1

1986 • 101 citations

Hypothalamo-Pituitary Regulation of Cytochrome P-450_15βApoprotein Levels in Rat Liver*

1985 • 97 citations

Growth hormone specifically regulates serine protease inhibitor gene transcription via gamma-activated sequence-like DNA elements

1994 • 80 citations

Dexamethasone enhancement of gene expression after direct hepatic DNA injection.

1994 • 78 citations

Down-Regulation of Liver JAK2-STAT5b Signaling by the Female Plasma Pattern of Continuous Growth Hormone Stimulation

1999 • 75 citations

Binding of STAT5a and STAT5b to a Single Element Resembling a γ-Interferon-Activated Sequence Mediates the Growth Hormone Induction of the Mouse Acid-Labile Subunit Promoter in Liver Cells

1998 • 67 citations

A STAT Factor Mediates the Sexually Dimorphic Regulation of Hepatic Cytochrome P450 3A10/Lithocholic Acid 6β-Hydroxylase Gene Expression by Growth Hormone

1995 • 65 citations

Pituitary regulation of sex-specific forms of cytochrome P-450 in liver microsomes of rats

1985 • 62 citations

Effects of Hypophysectomy and Growth Hormone Treatment on Sex-Specific Forms of Cytochrome P-450 in Relation to Drug and Steroid Metabolisms in Rat Liver Microsomes

1986 • 59 citations

Desensitization of the Growth Hormone-Induced Janus Kinase 2 (Jak 2)/Signal Transducer and Activator of Transcription 5 (Stat5)-Signaling Pathway Requires Protein Synthesis and Phospholipase C*

1998 • 50 citations

Interaction of a Novel Sex-dependent, Growth Hormone-regulated Liver Nuclear Factor with CYP2C12 Promoter

1996 • 48 citations

cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.

1988 • 45 citations

The Distal Enhancer Implicated in the Developmental Regulation of the Tyrosine Aminotransferase Gene Is Bound by Liver-Specific and Ubiquitous Factors

1993 • 36 citations

Growth Hormone Signaling Leading to CYP2C12 Gene Expression in Rat Hepatocytes Involves Phospholipase A2

1995 • 35 citations

CCAAT/enhancer-binding protein-alpha-dependent transactivation of CYP2C12 in rat hepatocytes.

1995 • 31 citations

Growth hormone regulates expression of rat liver cytochrome P-45015β at a pretranslational level

1987 • 27 citations

Characterization of Orphan Nuclear Receptor Binding Elements in Sex-differentiated Members of the cyp2c Gene Family Expressed in Rat Liver

1995 • 27 citations

Structural and Regulatory Analysis of a Cytochrome P450 Gene (CYP2C12) Expressed Predominantly in Female Rat Liver

1990 • 24 citations

Male-specific transcription initiation of theC4-Slpgene in mouse liver follows activation of STAT5

1998 • 20 citations

IRE-ABP (Insulin Response Element-A Binding Protein), an SRY-Like Protein, Inhibits C/EBPα (CCAAT/Enhancer-Binding Proteinα )-Stimulated Expression of the Sex-Specific Cytochrome P450 2C12 Gene

1998 • 16 citations