UV-induced CYP1A1 gene expression in human cells is mediated by tryptophan

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Circadian oscillation of a mammalian homologue of the Drosophila period gene

1997 • 782 citations

Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis.

1982 • 520 citations

Neurospora wc-1 and wc-2 : Transcription, Photoresponses, and the Origins of Circadian Rhythmicity

1997 • 494 citations

Twilight Times: Light and the Circadian System

1997 • 350 citations

Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances.

1987 • 340 citations

Induction of cytochrome P4501A1: a model for analyzing mammalian gene transcription

1996 • 245 citations

Activation of mammalian gene expression by the UV component of sunlight – from models to reality

1996 • 243 citations

Molecular biology of the aromatic hydrocarbon (dioxin) receptor

1994 • 234 citations

Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands

1995 • 202 citations

Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: its possible occurrence in cancer patients.

1986 • 191 citations

Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones.

1982 • 160 citations

New trends in photobiology

1993 • 152 citations

Rapid and transient induction of CYP1A1 gene expression in human cells by the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole

1998 • 150 citations

Formation of 8-hydroxydeoxyguanosine within DNA of mouse keratinocytes exposed in culture to UVB and H₂O₂

1992 • 127 citations

Oxidative Processes and Antioxidants

1995 • 100 citations

The mammalian UV response: Mechanism of DNA damage induced gene expression

1994 • 94 citations

Ultraviolet photoproducts of tryptophan can act as dioxin agonists.

1991 • 86 citations

Increase in p53 protein half-life in mouse keratinocytes following UV-B irradiation

1994 • 86 citations

Seasonal variation of aryl hydrocarbon hydroxylase activity in human lymphocytes.

1981 • 67 citations

The MurineCyp1a-1Gene Negatively Regulates Its Own Transcription and that of Other Members of the Aromatic Hydrocarbon-Responsive [Ah] Gene Battery

1990 • 59 citations

Additive Effects of Ultraviolet B and Crude Coal Tar on Cutaneous Carcinogen Metabolism: Possible Relevance to the Tumorigenicity of the Goeckerman Regimen

1986 • 55 citations

Ultraviolet radiation induction of ornithine decarboxylase in rat keratinocytes.

1990 • 45 citations

Induction of benzo[a]pyrene Mono-oxygenase in liver cell culture by the photochemical generation of active oxygen species. Evidence for the involvement of singlet oxygen and the formation of a stable inducing intermediate

1976 • 45 citations

Influence of UVA and UVB irradiation on hepatic and cutaneous P450 isoenzymes

1996 • 41 citations

Influence of chronic UV-light exposure on hepatic and cutaneous monooxygenases

1983 • 37 citations

Transient induction of cytochrome P450 1A1 mRNA by culture medium component in primary cultures of adult rat hepatocytes

1993 • 37 citations

The induction of benzo[a]pyrene-3-mono-oxygenase by singlet oxygen in liver cell culture is mediated by oxidation products of histidine

1980 • 34 citations

Effect of low-dose ultraviolet-B radiation on the function of human T lymphocytesin vitro

1993 • 29 citations

Induction of cytochrome P4501A1 by photooxidized tryptophan in Hepa lclc7 cells

1996 • 26 citations

UV-irradiation of tryptophan gives rise to AHH-inducing compounds with very high affinity for the Ah receptor

1989 • 12 citations

A mechanistic study of the interaction of UVB radiations with human serum lipoproteins

1991 • 12 citations