Cerebrospinal Fluid Concentrations and Serum Protein Binding of Lorazepam and its Conjugate

The importance of dissociaton constant and lipid-solubility in influencing the passage of drugs into the cerebrospinal fluid.

1960 • 256 citations

Mechanisms of Drug Absorption and Excretion Passage of Drugs in and out of the Central Nervous System

1962 • 147 citations

Analysis of lorazepam and its glucoronide metabolite by electron-capture gas—liquid chromatography

1978 • 99 citations

MEDICAL CARE AND FAMILY INCOME IN THE U.S.A.

1964 • 97 citations

BIOTRANSFORMATION AND EXCRETION OF LORAZEPAM IN PATIENTS WITH CHRONIC RENAL FAILURE

1976 • 71 citations

METABOLISM OF LORAZEPAM

1976 • 70 citations

Cerebrospinal‐Fluid Concentrations of Diazepam and its Metabolites in Man

1975 • 63 citations

Studies of sodium-potassium activated adenosine triphosphatase

1964 • 61 citations

Cumulation in Cerebrospinal Fluid of the N‐desmethyl Metabolite after Long‐term Treatment with Diazepam in Man

1975 • 21 citations

Plasma and cerebrospinal fluid concentrations of chlordiazepoxide and its metabolites in surgical patients

1976 • 20 citations

CONCENTRATION OF DIGOXIN IN CHOROID PLEXUS

1973 • 19 citations

Cerebrospinal-fluid Concentrations of Nitrazepam in Man

1977 • 17 citations

Pilot clinical trial of parenteral lorazepam (Temesta�) in anxiety states

1973 • 10 citations