Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients.

Determination of plasma catecholamines by high performance liquid chromatography with electrochemical detection: Comparison with a radioenzymatic method

1979 • 579 citations

Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man.

1987 • 519 citations

ON DIABETIC ACIDOSIS

1933 • 397 citations

Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus.

1976 • 370 citations

Inhibition by Insulin of Valine Turnover in Liver

1970 • 338 citations

A microfluorometric method for the determination of free fatty acids in plasma

1983 • 336 citations

Comparison of acid ethanol extraction and acid gel filtration prior to IGF-I and IGF-II radioimmunoassays: Improvement of determinations in acid ethanol extracts by the use of truncated IGF-I as radioligand

1991 • 315 citations

Regulation by insulin of amino acid release and protein turnover in the perfused rat hemicorpus.

1977 • 294 citations

Cross-reaction of serum somatomedin-binding protein in a radioimmunoassay developed for somatomedin-binding protein isolated from human amniotic fluid

1984 • 266 citations

Isotopic analysis of leucine and urea metabolism in exercising humans

1982 • 240 citations

Use of t-butyldimethylsilylation in the gas chromatographic/mass spectrometric analysis of physiologic compounds found in plasma using electron-impact ionization

1984 • 238 citations

Role of Insulin in the Regulation of Protein Synthesis

1980 • 234 citations

Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans

1992 • 224 citations

Effect of Streptozotocin Diabetes and Insulin Treatment on the Rate of Protein Synthesis in Tissues of the Rat in Vivo

1974 • 220 citations

Rapid measurement of whole body and forearm protein turnover using a [2H5]phenylalanine model

1989 • 203 citations

Effect of poor diabetic control and obesity on whole body protein metabolism in man

1983 • 194 citations

Regulation of Leucine Metabolism in Man: A Stable Isotope Study

1981 • 189 citations

Differential effects of insulin deficiency on albumin and fibrinogen synthesis in humans.

1991 • 174 citations

Insulin sensitivity of protein and glucose metabolism in human forearm skeletal muscle.

1992 • 168 citations

ROLES OF INSULIN AND GROWTH HORMONE, BASED ON STUDIES ON FOREARM METABOLISM IN MAN

1963 • 168 citations

Isolation of aminoacyl-tRNA and its labeling with stable-isotope tracers: Use in studies of human tissue protein synthesis.

1991 • 167 citations

Amino acids augment insulin's suppression of whole body proteolysis

1989 • 149 citations

Amino Acid and Protein Metabolism in Diabetes Mellitus

1977 • 142 citations

Precursor pools of protein synthesis: a stable isotope study in a swine model

1994 • 134 citations

Analysis of (1-13C)leucine and (13C)KIC in plasma by capillary gas chromatography/mass spectrometry in protein turnover studies

1985 • 126 citations

Increased energy expenditure in poorly controlled Type 1 (insulin-dependent) diabetic patients

1984 • 119 citations

Influence of Leucine on Arterial Concentrations and Regional Exchange of Amino Acids in Healthy Subjects

1980 • 108 citations

Proteolysis in skeletal muscle and whole body in response to euglycemic hyperinsulinemia in normal adults

1991 • 105 citations

Effect of intravenous insulin treatment on in vivo whole body leucine kinetics and oxygen consumption in insulin-deprived type I diabetic patients

1987 • 97 citations

Defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. Evidence for insulin resistance involving glucose and amino acid metabolism.

1986 • 95 citations

Protein metabolism in skeletal muscle, diaphragm, and heart of diabetic rats

1983 • 88 citations

Leucine Metabolism in IDDM: Role of Insulin and Substrate Availability

1990 • 87 citations

Response of protein synthesis in human skeletal muscle to insulin: an investigation with L-[2H5]phenylalanine

1994 • 87 citations

THE EFFECT OF INSULIN ON THE AMINO ACID CONTENT OF BLOOD

1928 • 86 citations

Free and total insulin as determined after precipitation with polyethylene glycol: analytical characteristics and effects of sample handling and storage.

1987 • 86 citations

Protein synthesis in liver and small intestine in protein deprivation and diabetes

1981 • 85 citations

Failure of Insulin Infusion to Stimulate Fractional Muscle Protein Synthesis in Type I Diabetic Patients: Anabolic Effect of Insulin and Decreased Proteolysis

1989 • 84 citations

Effect of hyperinsulinemia on whole body and skeletal muscle leucine carbon kinetics in humans

1992 • 82 citations

Differential compartmentation of leucine for oxidation and for protein synthesis in cultured skeletal muscle.

1981 • 80 citations

Attenuated responses of muscle protein synthesis to fasting and insulin in adult female rats

1992 • 71 citations

Measurement of L-[1-14C]Leucine Kinetics in Splanchnic and Leg Tissues In Humans: Effect of Amino Acid Infusion

1988 • 68 citations

Sample site selection for tracer studies applying a unidirectional circulatory approach

1987 • 63 citations

Whole Body De Novo Amino Acid Synthesis in Type I (Insulin-dependent) Diabetes Studied With Stable Isotope-labeled Leucine, Alanine, and Glycine

1985 • 60 citations

Growth Hormone Binding Proteins and Various Forms of Growth Hormone: Implications for Measurements

1990 • 52 citations

Effect of systemic hyperinsulinemia on amino acid flux across human legs in postabsorptive state

1991 • 49 citations

Activation of rat liver branched-chain 2-oxo acid dehydrogenase in vivo by glucagon and adrenaline

1985 • 35 citations

Leucine metabolism in IDDM. Role of insulin and substrate availability

1990 • 35 citations

Studies in whole body potassium and whole body nitrogen in newly diagnosed diabetics.

1976 • 30 citations

Whole body de novo amino acid synthesis in type I (insulin-dependent) diabetes studied with stable isotope-labeled leucine, alanine, and glycine

1985 • 18 citations

Discordant metabolic actions of insulin in extreme lipodystrophy of childhood.

1993 • 16 citations

Studies in Whole Body Potassium and Whole Body Nitrogen in Newly Diagnosed Diabetics

1976 • 15 citations

Energy and protein metabolism in diabetes and obesity.

1984 • 12 citations

Influence of insulin on albumin and non-albumin protein fractional synthetic rates in post-absorptive type I diabetic patients.

1990 • 11 citations

Discordant metabolic actions of insulin in extreme lipodystrophy of childhood

1993 • 9 citations