Functional activity of murine CD34+and CD34− hematopoietic stem cell populations

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

1996 • 2,901 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell

1996 • 2,160 citations

High-Resolution Mapping of Human Chromosome 11 by in Situ Hybridization with Cosmid Clones

1990 • 1,357 citations

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species

1997 • 1,116 citations

CD34: structure, biology, and clinical utility [see comments]

1996 • 891 citations

Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

1997 • 879 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 699 citations

CD34: structure, biology, and clinical utility [see comments]

1996 • 690 citations

A newly discovered class of human hematopoietic cells with SCID-repopulating activity

1998 • 640 citations

Antigen CD34+ marrow cells engraft lethally irradiated baboons.

1988 • 608 citations

Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma

1991 • 538 citations

In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells

1992 • 520 citations

Separation of pluripotent haematopoietic stem cells from spleen colony-forming cells

1990 • 414 citations

Human bone marrow CD34- cells engraft in vivo and undergo multilineage expression that includes giving rise to CD34+ cells.

1998 • 346 citations

Isolation of murine pluripotent hemopoietic stem cells.

1984 • 333 citations

Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells

1994 • 274 citations

In vivo and in vitro characterization of long-term repopulating primitive hematopoietic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection.

1993 • 271 citations

Kinetic Evidence of the Regeneration of Multilineage Hematopoiesis From Primitive Cells in Normal Human Bone Marrow Transplanted Into Immunodeficient Mice

1997 • 247 citations

Engraftment and Development of Human CD34+-Enriched Cells From Umbilical Cord Blood in NOD/LtSz-scid/scid Mice

1997 • 215 citations

Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells

1994 • 210 citations

Characterization of mouse lymphohematopoietic stem cells lacking spleen colony-forming activity

1996 • 199 citations

The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts

1991 • 188 citations

Selection and expansion of peripheral blood CD34+ cells in autologous stem cell transplantation for breast cancer

1996 • 184 citations

The stem cell system.

1983 • 166 citations

Transplantation of allogeneic CD34+ peripheral blood stem cells in patients with advanced hematologic malignancy

1996 • 163 citations

CD34+ human marrow cells that express low levels of Kit protein are enriched for long-term marrow-engrafting cells

1996 • 160 citations

Highly purified CD34-positive cells reconstitute hematopoiesis.

1996 • 159 citations

CD34+ marrow cells, devoid of T and B lymphocytes, reconstitute stable lymphopoiesis and myelopoiesis in lethally irradiated allogeneic baboons

1992 • 144 citations

High doses of purified stem cells cause early hematopoietic recovery in syngeneic and allogeneic hosts.

1998 • 140 citations

Long-term generation and expansion of human primitive hematopoietic progenitor cells in vitro

1993 • 135 citations

Human CD34+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis.

1991 • 132 citations

CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein

1996 • 130 citations

Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34

1994 • 122 citations

Transplantation of allogeneic CD34+ peripheral blood stem cells in patients with advanced hematologic malignancy

1996 • 122 citations

What defines a pluripotent hematopoietic stem cell (PHSC): will the real PHSC please stand up! [editorial]

1994 • 121 citations

CD34 positive PBPC expanded ex vivo may not provide durable engraftment following myeloablative chemoradiotherapy regimens

1997 • 112 citations

Full-length but not truncated CD34 inhibits hematopoietic cell differentiation of M1 cells

1995 • 101 citations

Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil- treated murine marrow

1993 • 97 citations

Isolation of primitive human bone marrow hematopoietic progenitor cells using Hoechst 33342 and Rhodamine 123.

1996 • 95 citations

Primitive hematopoietic cells in murine bone marrow express the CD34 antigen

1996 • 95 citations

Equal distribution of competitive long-term repopulating stem cells in the CD34+ and CD34- fractions of Thy-1lowLin-/lowSca-1+ bone marrow cells.

1998 • 93 citations

Two types of murine CD34 mRNA generated by alternative splicing

1992 • 69 citations

Antitheta-sensitive regulatory cell (TSRC) and hematopoiesis: regulation of differentiation of transplanted stem cells in W/Wv anemic and normal mice

1978 • 60 citations

Identification of CD34+ subsets after glycoprotease selection: engraftment of CD34+Thy-1+Lin- stem cells in fetal sheep.

1996 • 58 citations

Short- and long-term repopulation of lethally irradiated mice by bone marrow stem cells enriched on the basis of light scatter and Hoechst 33342 fluorescence.

1991 • 51 citations

Expansion in bioreactors of human progenitor populations from cord blood and mobilized peripheral blood.

1994 • 45 citations

Cord blood as an alternative source for stem and progenitor cell transplantation

1995 • 34 citations

Separation and concentration of murine hematopoietic stem cells (CFUS) using a combination of density gradient sedimentation and counterflow centrifugal elutriation.

1981 • 24 citations

Detection of nondisjunction and recombination in meiotic and postmeiotic cells from XYSxr [XY,Tp(Y)1Ct] mice using multicolor fluorescence in situ hybridization.

1994 • 22 citations

Rapid engraftment after allogeneic transplantation using CD34-enriched marrow cells

1998 • 20 citations

Stem cell is a stem cell is a stem cell

1983 • 18 citations

Transplantation of allogeneic CD34+ peripheral blood stem cells (PBSC) in patients with advanced hematologic malignancy.

1996 • 8 citations

IN VITRO (EX VIVO) EXPANSION OF MURINE HEMATOPOIETIC STEM CELLS Running Title: In Vitro Expansion of Stem Cells

1996 • 1 citations