Phosphorylation of two regulatory tyrosine residues in the activation of Bruton’s tyrosine kinase via alternative receptors

Antibodies, a laboratory manual

1989 • 12,929 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

1993 • 1,438 citations

Three-dimensional structure of the tyrosine kinase c-Src

1997 • 1,402 citations

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

1993 • 1,338 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

Crystal structure of the Src family tyrosine kinase Hck

1997 • 1,165 citations

Structural basis for the binding of proline-rich peptides to SH3 domains

1994 • 1,016 citations

Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice

1993 • 868 citations

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

1993 • 817 citations

Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions

1994 • 800 citations

Colocalization of X-Linked Agammaglobulinemia and X-Linked Immunodeficiency Genes

1993 • 631 citations

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

1995 • 597 citations

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

1996 • 560 citations

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

1994 • 519 citations

Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells.

1990 • 487 citations

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

1991 • 471 citations

Activation of BTK by a Phosphorylation Mechanism Initiated by SRC Family Kinases

1996 • 445 citations

Immunodeficiency in Protein Kinase Cβ-Deficient Mice

1996 • 444 citations

Signal Transduction by the B Cell Antigen Receptor and its Coreceptors

1994 • 419 citations

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.

1994 • 322 citations

Regulation of Btk Function by a Major Autophosphorylation Site Within the SH3 Domain

1996 • 321 citations

Regulatory intramolecular association in a tyrosine kinase of the Tec family

1997 • 274 citations

Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement.

1994 • 250 citations

Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia

1997 • 240 citations

Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking.

1994 • 221 citations

Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin.

1993 • 208 citations

The B-cell antigen receptor complex: structure and signal transduction

1994 • 204 citations

Structure‐function relationships in Src family and related protein tyrosine kinases

1995 • 201 citations

Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells.

1994 • 196 citations

Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin.

1993 • 194 citations

Activation of bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain

1995 • 191 citations

B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemia.

1994 • 187 citations

BAP-135, a target for Bruton’s tyrosine kinase in response to B cell receptor engagement

1997 • 182 citations

IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases.

1994 • 178 citations

Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction.

1994 • 172 citations

Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines

1995 • 160 citations

Vertebrate non‐receptor protein–tyrosine kinase families

1996 • 154 citations

Src Family Protein Tyrosine Kinases Induce Autoactivation of Bruton's Tyrosine Kinase

1995 • 151 citations

Bruton’s tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

1997 • 137 citations

Structure of the Pl3K SH3 domain and analysis of the SH3 family

1993 • 137 citations

The activation of the Jak-STAT 1 signaling pathway by IL-5 in eosinophils.

1995 • 131 citations

The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase.

1995 • 131 citations

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

1997 • 127 citations

Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits.

1995 • 127 citations

Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha

1995 • 125 citations

Regulation of Btk by Src Family Tyrosine Kinases

1996 • 106 citations

NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos

1994 • 104 citations

Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos

1994 • 97 citations

CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regulator of CD38 induced signal transduction

1995 • 87 citations

A New Monoclonal Antibody Which Selectively Recognizes the Active Form of Src Tyrosine Kinase

1996 • 87 citations

IL-5 receptor positive B cells, but not eosinophils, are functionally and numerically influenced in mice carrying the X-linked immune defect

1993 • 68 citations

Synthetic phosphopeptide immunogens yield activation-specific antibodies to the c-erbB-2 receptor.

1992 • 57 citations

Tyrosine Phosphorylation and Activation of Bruton Tyrosine Kinase upon FceRI Cross-Linking

1994 • 53 citations

Defective IL-5-receptor-mediated signaling in B cells of X-linked immunodeficient mice

1995 • 52 citations

Signal transduction in the activation of mast cells and basophils

1995 • 49 citations

Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor.

1992 • 46 citations

A monoclonal antibody against a murine CD38 homologue delivers a signal to B cells for prolongation of survival and protection against apoptosis in vitro: unresponsiveness of X-linked immunodeficient B cells.

1995 • 42 citations

Immortalization of Mouse Bone Marrow-Derived Mast Cells with Ad12-SV40 Virus

1993 • 31 citations

The protein defective in X‐linked agammaglobulinemia, Bruton's tyrosine kinase, shows increased autophosphorylation activity in vitro when isolated from cells in which the B cell receptor has been cross‐linked

1995 • 19 citations

Monoclonal Antibodies as Site-Specific Probes for the Acetylcholine-receptor delta-Subunit Tyrosine and Serine Phosphorylation Sites

1995 • 7 citations

Monoclonal Antibodies as Site-Specific Probes for the Acetylcholine-receptor delta-Subunit Tyrosine and Serine Phosphorylation Sites

1995 • 4 citations

Spontaneous Degranulation of Cultured Bone-Marrow-Derived Immature Mast Cells from X-Linked Immunodeficient (Xid) Mice

1996 • 4 citations