Endothelin Family in Human Plasma and Cerebrospinal Fluid

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Integrated cardiac, renal, and endocrine actions of endothelin.

1989 • 481 citations

Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.

1989 • 413 citations

Sarafotoxin, a Novel Vasoconstrictor Peptide: Phosphoinositide Hydrolysis in Rat Heart and Brain

1988 • 362 citations

Abundance of endothelin-3 in rat intestine, pituitary gland and brain

1989 • 346 citations

Immunoreactive endothelin in human plasma: Marked elevations in patients in cardiogenic shock

1989 • 330 citations

Endothelin: A Novel Peptide in the Posterior Pituitary System

1990 • 313 citations

Autoradiographic distribution in rat tissues of binding sites for endothelin: a neuropeptide?

1989 • 299 citations

A sensitive sandwich-enzyme immunoassay for human endothelin

1989 • 298 citations

PLASMA ENDOTHELIN LEVELS IN PATIENTS WITH URAEMIA

1989 • 292 citations

Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs

1988 • 279 citations

Atrial natriuretic factor in human blood.

1985 • 252 citations

Autoradiographic visualization of the binding sites for [125I]endothelin in rat and human brain

1989 • 225 citations

THE CEREBROSPINAL FLUID AS A PATHWAY IN NEUROENDOCRINE INTEGRATION

1976 • 194 citations

Endothelin-3 is a novel neuropeptide: Isolation and sequence determination of endothelin-1 and endothelin-3 in porcine brain

1989 • 142 citations

Endothelin localizes in the dorsal horn and acts on the spinal neurones: Possible involvement of dihydropyridine-sensitive calcium channels and substance P release

1989 • 134 citations

Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect in vivo

1989 • 126 citations

Presence of endothelin-1 in porcine spinal cord: Isolation and sequence determination

1989 • 92 citations

Production of Endothelin-1 and Big-Endothelin-1 by Tumor Cells with Epithelial-Like Morphology

1989 • 56 citations

A sandwich-type enzyme immunoassay to detect immunoreactive big-endothelin-1 in plasma

1990 • 44 citations

Neuropeptides in the cerebrospinal fluid

1984 • 12 citations