Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1996 • 1,505 citations

Practical methods for biological morphometry

1979 • 1,498 citations

Stereological Methods

1982 • 1,198 citations

A Lesson in Metabolic Regulation Inspired by the Glucokinase Glucose Sensor Paradigm

1996 • 728 citations

Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression.

1996 • 413 citations

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression.

1995 • 400 citations

Cellular composition of the human diabetic pancreas

1983 • 394 citations

β-Cell Dysfunction Induced by Chronic Hyperglycemia: Current Ideas on Mechanism of Impaired Glucose-Induced Insulin Secretion

1992 • 356 citations

Diabetic Hyperglycemia: Link to Impaired Glucose Transport in Pancreatic β Cells

1991 • 260 citations

The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment.

1992 • 166 citations

Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats.

1990 • 158 citations

Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion. Relationship to glucose metabolism

1993 • 154 citations

Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas.

1994 • 151 citations

The Insulin Gene Contains Multiple Transcriptional Elements That Respond to Glucose

1994 • 145 citations

Nutrient regulation of insulin gene expression

1994 • 142 citations

A novel signal transduction pathway in Saccharomyces cerevisiae defined by Snf3-regulated expression of HXT6.

1996 • 141 citations

Molecular and Cellular Physiology of GLUT-2, a High-KmFacilitated Diffusion Glucose Transporter

1992 • 125 citations

Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: Inactivation of the mouseERCC-1 gene

1992 • 111 citations

Expression of GLUT-2 antisense RNA in beta cells of transgenic mice leads to diabetes.

1994 • 85 citations

The insulin gene contains multiple transcriptional elements that respond to glucose.

1994 • 83 citations

Impairment of Glycerol Phosphate Shuttle in Islets From Rats With Diabetes Induced by Neonatal Streptozocin

1991 • 76 citations

Development of the biphasic response to glucose in fetal and neonatal rat pancreas

1988 • 68 citations

Glucose-stimulated DNA Replication of the Pancreatic Islets During the Development of the Rat Fetus: Effects of Nutrients, Growth Hormone, and Triiodothyronine

1985 • 59 citations

Development of Insulin Release by Fetal Rat Pancreas In Vitro: Effects of Glucose, Amino Acids, and Theophylline

1980 • 58 citations

Differences in insulin secretion between the rat and mouse: role of cAMP

1995 • 55 citations

Deficiency of pyruvate dehydrogenase activity in pancreatic islets of diabetic GK rats.

1995 • 52 citations

Standardization of Insulin Secretion from Pancreatic Islets: Validation of a DNA Assay

1985 • 42 citations

[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis.

1992 • 42 citations

Sequence of the mouse liver glucose transporter

1989 • 34 citations

Insulin Gene Transcription Is Decreased Rapidly by Lowering Glucose Concentrations in Rat Islet Cells

1994 • 20 citations