Pathologic findings associated with interleukin-2—Based immunotherapy for cancer: A postmortem study of 19 patients

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

1987 • 2,769 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Experience with the Use of High-Dose Interleukin-2 in the Treatment of 652 Cancer Patients

1989 • 1,003 citations

Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli

1984 • 600 citations

Metastatic Renal Cancer Treated with Interleukin-2 and Lymphokine-Activated Killer Cells

1988 • 353 citations

Hypothyroidism after Treatment with Interleukin-2 and Lymphokine-Activated Killer Cells

1988 • 321 citations

Cardiorespiratory effects of immunotherapy with interleukin-2.

1989 • 246 citations

Effects of Interleukin-2 on Renal Function in Patients Receiving Immunotherapy for Advanced Cancer

1987 • 170 citations

Dermatologic Changes Associated With Interleukin 2 Administration

1987 • 142 citations

The Hemodynamic Effects of Treatment with Interleukin-2 and Lymphokine-Activated Killer Cells

1988 • 118 citations

A prospective randomized trial evaluating prophylactic antibiotics to prevent triple-lumen catheter-related sepsis in patients treated with immunotherapy.

1990 • 105 citations

Myocardial Toxic Effects During Recombinant Interleukin-2 Therapy

1989 • 80 citations

Acute immunologic effects of interleukin-2 therapy in cancer patients: decreased delayed type hypersensitivity response and decreased proliferative response to soluble antigens.

1988 • 73 citations

Interleukin-2 induces profound reversible cholestasis: a detailed analysis in treated cancer patients.

1989 • 71 citations

Fournier gangrene: diagnosis with scrotal US.

1988 • 59 citations

IL-2-based immunotherapy alters circulating neutrophil Fc receptor expression and chemotaxis.

1990 • 57 citations

Toxicity of recombinant human interleukin-2 in rats following intravenous infusion.

1985 • 54 citations

Severe myocarditis following high-dose interleukin-2 administration.

1989 • 52 citations

Decrease in interleukin 2-induced vascular leakage in the lungs of mice by administration of recombinant interleukin 1 alpha in vivo.

1989 • 38 citations

Colonic perforation: An unusual complication of therapy with high-dose lnterleukin-2

1988 • 35 citations

Dermatologic changes associated with interleukin 2 administration

1987 • 21 citations

A Phase I Study of Recombinant Interleukin 2 in Melanoma Patients. Toxicity and Clinical Effects

1987 • 21 citations

MYOCARDIAL INJURY AFTER INTERLEUKIN-2 THERAPY

1988 • 21 citations