Inhibition of Histone Deacetylation Augments Dihydrotestosterone Induction of Androgen Receptor Levels: An Explanation for Trichostatin A Effects on Androgen-Induced Chromatin Remodeling and Transcription of the Mouse Mammary Tumor Virus Promoter

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

1990 • 1,835 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 • 1,251 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 • 1,218 citations

Chromatin Structure and Function

1979 • 1,050 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

1984 • 449 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones.

1992 • 430 citations

Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability.

1995 • 393 citations

Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo.

1995 • 313 citations

The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor

1998 • 264 citations

Transcriptional Regulation of Mammalian Genes in Vivo

1997 • 244 citations

Androgen increases androgen receptor protein while decreasing receptor mRNA in LNCaP cells

1991 • 192 citations

Chromatin structure and function

1994 • 180 citations

Domains of the Glucocorticoid Receptor Involved in Specific and Nonspecific Deoxyribonucleic Acid Binding, Hormone Activation, and Transcriptional Enhancement

1987 • 174 citations

Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability

1995 • 173 citations

Nucleosome positioning on the MMTV LTR results from the frequency-biased occupancy of multiple frames.

1995 • 171 citations

Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase

1998 • 161 citations

Prolonged glucocorticoid exposure dephosphorylates histone H1 and inactivates the MMTV promoter

1998 • 144 citations

Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate.

1990 • 135 citations

Mechanism of androgen-receptor augmentation. Analysis of receptor synthesis and degradation by the density-shift technique.

1985 • 132 citations

Nucleosome-mediated disruption of transcription factor-chromatin initiation complexes at the mouse mammary tumor virus long terminal repeat in vivo.

1994 • 128 citations

A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cells

1997 • 107 citations

Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure.

1996 • 97 citations

Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter.

1994 • 87 citations

The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells.

1994 • 65 citations

Differential Activity of Progesterone and Glucocorticoid Receptors on Mouse Mammary Tumor Virus Templates Differing in Chromatin Structure

1997 • 52 citations

Regulation of the 5'-flanking region of the mouse androgen receptor gene by cAMP and androgen.

1993 • 51 citations

Isolation and characterization of a mouse L cell variant deficient in glucocorticoid receptors

1989 • 32 citations

Comparison of Chromatin Remodeling and Transcriptional Activation of the Mouse Mammary Tumor Virus Promoter by the Androgen and Glucocorticoid Receptor

1999 • 25 citations

The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells

1994 • 24 citations

Regulation of the 5'-flanking region of the mouse androgen receptor gene by cAMP and androgen

1993 • 20 citations

Identification of Glucocorticoid Receptor Domains Necessary for Transcriptional Activation of the Mouse Mammary Tumor Virus Promoter Integrated in the Genome

1998 • 12 citations

Modulation of Transcription Factor Access and Activity at the MMTV Promoter In Vivo

1995 • 9 citations