Development of catecholaminergic phenotypic characters in the mouse locus coeruleus in vivo and in culture

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

Estimation of nuclear population from microtome sections

1946 • 4,378 citations

Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*

1971 • 3,816 citations

Tyrosine Hydroxylase

1964 • 2,038 citations

Nerve growth factor.

1968 • 2,025 citations

The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine‐B‐hydroxylase as a marker

1975 • 1,454 citations

Frontiers in Catecholamine Research

1973 • 1,252 citations

Ascending Monoamine Neurons to the Telencephalon and Diencephalon

1966 • 1,205 citations

The organization of the ascending catecholamine neuron systems in the rat brain as revealed by the glyoxylic acid fluorescence method.

1974 • 1,130 citations

Tissue Culture. Methods and Applications

1974 • 1,068 citations

ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART.

1965 • 1,002 citations

Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study

1977 • 835 citations

The Migration and Differentiation of Neural Crest Cells

1970 • 814 citations

CATECHOLAMINES IN FETAL AND NEWBORN RAT BRAIN

1973 • 785 citations

The Nerve Growth Factor: Biochemistry, Synthesis, and Mechanism of Action

1980 • 733 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat. I. Cell differentiation

1974 • 653 citations

Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein

1960 • 651 citations

Late prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations

1973 • 651 citations

Environmental Determination of Autonomic Neurotransmitter Functions

1978 • 550 citations

Importance of fixation in immunohistochemistry: use of formaldehyde solutions at variable pH for the localization of tyrosine hydroxylase.

1981 • 506 citations

A radioautographic study of the efferent pathways of the nucleus locus coeruleus

1974 • 500 citations

Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. II. Late ontogeny

1981 • 497 citations

Early prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations

1972 • 497 citations

B. TYROSINE HYDROXYLASE

1966 • 493 citations

On the projections from the locus coeruleus noradrenaline neurons: The cerebellar innervation

1971 • 477 citations

A new major projection from locus coeruleus: The main source of noradrenergic nerve terminals in the ventral and dorsal columns of the spinal cord

1977 • 476 citations

Neurosecretion and Brain Peptides

1982 • 458 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat

1975 • 411 citations

Increase in tyrosine hydroxylase activity after reserpine administration.

1969 • 354 citations

Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny

1981 • 349 citations

Trophic Mechanisms in the Peripheral Nervous System

1978 • 326 citations

Elevation of Adrenal Tyrosine Hydroxylase and Phenylethanolamine-N-Methyl Transferase by Repeated Immobilization of Rats

1970 • 316 citations

Tyrosine hydroxylase in rat brain—cofactor requirements, regional and subcellular distribution

1972 • 308 citations

Trans-synaptic regulation of growth and development of adrenergic neurones in a mouse sympathetic ganglion

1971 • 296 citations

Purification and characterization of tyrosine hydroxylase from a clonal pheochromocytoma cell line.

1980 • 292 citations

Trans-synaptic induction of adrenal tyrosine hydroxylase.

1969 • 283 citations

Dopamine-beta-hydroxylase.

1980 • 283 citations

Noradrenaline neuron innervation of the neocortex in the rat

1978 • 265 citations

Cellular localization of tyrosine hydroxylase by immunohistochemistry.

1975 • 264 citations

TYROSINE HYDROXYLASE IN RAT BRAIN: DEVELOPMENTAL CHARACTERISTICS

1972 • 258 citations

Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path

1976 • 256 citations

DEVELOPMENT OF THE UPTAKE AND STORAGE OF L‐[³H]NOREPINEPHRINE IN THE RAT BRAIN

1971 • 240 citations

DOPAMINE-?-HYDROXYLASE IN THE RAT BRAIN: DEVELOPMENTAL CHARACTERISTICS

1972 • 228 citations

Ascending projections of the locus coeruleus in the rat. I. axonal transport in central noradrenaline neurons

1977 • 224 citations

Development of the noradrenergic innervation of neocortex

1979 • 212 citations

chapter 2 Migration and Differentiation of Neural Crest Cells

1980 • 203 citations

Appearance of catecholamine-synthesizing enzymes during development of rat sympathetic nervous system: Possible role of tissue environment

1979 • 189 citations

Increased tyrosine hydroxylase activity in the locus coeruleus of rat brain stem after reserpine treatment and cold stress

1974 • 186 citations

PROPERTIES OF NOREPINEPHRINE STORAGE PARTICLES OF THE RAT HEART.

1963 • 174 citations

Role of glucocorticoids in expression of the adrenergic phenotype in rat embryonic adrenal gland

1981 • 158 citations

Biochemical Aspects of Neurotransmission in the Developing Brain

1977 • 156 citations

Prenatal development of the biogenic amine systems of the mouse brain

1973 • 128 citations

Hormonal control of neurotransmitter choice in sympathetic neurone cultures

1980 • 128 citations

Immunohistochemical studies on monoamine-containing cell systems

1973 • 125 citations

Stages of Neurotransmitter Development in Autonomic Neurons

1982 • 123 citations

Reserpine selectively increases tyrosine hydroxylase and dopamine-β-hydroxylase enzyme protein in central noradrenergic neurons

1974 • 123 citations

Membrane proteins of chromaffin granules. Dopamine β-hydroxylase, a major constituent

1972 • 113 citations

Trans-synaptic enzyme induction

1974 • 112 citations

Localization of different steps in noradrenaline synthesis to different fractions of a bovine splenic nerve homogenate

1967 • 110 citations

Trans-synaptic regulation of adrenergic neuron development: Inhibition by ganglionic blockade

1973 • 104 citations

Organotypic Mammalian Central and Peripheral Nerve Tissue11The research in the author's laboratory is supported by grants from the National Institute of Neurological Diseases and Stroke, The National Multiple Sclerosis Society, and The Sloan Foundation.

1973 • 99 citations

Increased tyrosine hydroxylase activity in frontal cortex and cerebellum after reserpine

1975 • 90 citations

Modification of norepinephrine synthesis in intact tissue dy drugs and during short-term adrenergic nerve stimulation.

1972 • 88 citations

Isolated catecholaminergic projections from substantia nigra and locus coeruleus to caudate, hippocampus and cerebral cortex formed by intraocular sequential double brain grafts

1979 • 88 citations

Methylazoxymethanol Treatment of Fetal Rats Results in Abnormally Dense Noradrenergic Innervation of Neocortex

1979 • 81 citations

Expression of phenylethanolamine N-methyltransferase in rat sympathetic ganglia and extra-adrenal chromaffin tissue

1982 • 73 citations

From the Neural Crest to the Ganglia of the Peripheral Nervous System

1981 • 70 citations

Glucocorticosteroids modulate transmitter choice in developing superior cervical ganglion

1980 • 69 citations

Noradrenergic neurons: Allosteric activation of hippocampal tyrosine hydroxylase by stimulation of the locus coeruleus

1974 • 64 citations

Failure of nerve growth factor to affect fetal mouse brain stem catecholaminergic neurons in culture

1980 • 62 citations

Accumulation of tyrosine hydroxylase molecules during growth and development of the superior cervical ganglion

1974 • 60 citations

INHIBITION OF THE BIOCHEMICAL AND MORPHOLOGICAL MATURATION OF ADRENERGIC NEURONS BY NICOTINIC RECEPTOR BLOCKADE

1974 • 58 citations

Effect of Hypophysectomy on Immobilization-Induced Elevation of Tyrosine Hydroxylase and Phenylethanolamine-N-methyl Transferase in the Rat Adrenal

1970 • 56 citations

Neurotransmitter synthetic enzymes

1973 • 55 citations

Innervation of hippocampal explants by central catecholaminergic neurons in co-cultured fetal mouse brain stem explants

1979 • 54 citations

Mechanism of secretion from the adrenal medulla. 3. Studies of dopamine beta-hydroxylase as a marker for catecholamine storage vesicle membranes in rabbit adrenal glands.

1969 • 54 citations

Evidence for the presence of dopamine‐β‐hydroxylase in both populations of noradrenaline storage vesicles in sympathetic nerve terminals of the rat vas deferens

1973 • 54 citations

Biosynthesis of adrenaline and noradrenaline.

1959 • 54 citations

Ontogeny of the noradrenergic innervation of the rat hippocampal formation

1979 • 45 citations

Explant cultures of catecholamine-containing neurons from rat brain: Biochemical, histofluorescence, and electron microscopic studies

1977 • 44 citations

Maternal Glucocorticoid Hormones Influence Neurotransmitter Phenotypic Expression in Embryos

1980 • 40 citations

Morphological and biochemical studies on the ontogenesis of the nucleus locus coeruleus.

1981 • 37 citations

Mechanisms involved in the trans-synaptic increase of tyrosine hydroxylase and dopamine-?-hydroxylase activity in sympathetic ganglia

1973 • 28 citations

A Coeruleo-Spinal System in Culture

1981 • 23 citations

Endogenous inhibitors of dopamine-β-hydroxylase in rat organs

1976 • 22 citations

Uptake of3H-noradrenaline and3H-5-hydroxytryptamine in cultured rat brainstem

1975 • 21 citations

Differential rates of increase in pontine tyrosine hydroxylase and dopamine-β-hydroxylase activities after reserpine

1975 • 11 citations

Tyrosine hydroxylase activity in the catecholamine nerve terminals and cell bodies of the rat brain

1977 • 10 citations

The early outgrowth of catecholaminergic fibers and the development of the nucleus of the locus coeruleus in tissue culture of newborn mice in Leighton tubes.

1979 • 9 citations

ROLE OF CATECHOLAMINES IN INDUCTION OF ADRENAL TYROSINE HYDROXYLASE

1973 • 4 citations

Regulation of noradrenergic and peptidergic development: a search for common mechanisms.

1981 • 3 citations