Effect of rifampicin.treatment on the metabolism of oestradiol and 17?-ethinyloestradiol by human liver microsomes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Rifampicin: A New Orally Active Rifamycin

1966 • 264 citations

CHANGES IN CORTISOL METABOLISM FOLLOWING RIFAMPICIN THERAPY

1974 • 211 citations

[109] Methods for the elevation of hepatic microsomal mixed function oxidase levels and cytochrome P-450

1967 • 168 citations

Comparison of activities of drug‐metabolizing enzymes in human fetal and adult livers

1973 • 119 citations

Metabolism and mechanism of action of oestrogens XII. Structure and mechanism of formation of water-soluble and protein-bound metabolites of oestrone in rat-liver microsomes in vitro and in vivo

1969 • 94 citations

Effect of Thyroid on Hydroxylation of Estrogen in Man

1965 • 93 citations

Wirkung von Rifampicin auf den Menstruationszyklus und die Östrogenausscheidung bei Einnahme oraler Kontrazeptiva

1973 • 90 citations

Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro

1973 • 79 citations

Aromatic ring hydroxylation of estradiol in man

1970 • 79 citations

Irreversile binding of ethynyl-estradiol metabolites to protein and nucleic acids as catalyzed by rat liver microsomes and mushroom tyrosinas

1974 • 76 citations

Metabolism of 17α-Ethinylestradiol by Human Liver Microsomesin Vitro: Aromatic Hydroxylation and Irreversible Protein Binding of Metabolites

1974 • 76 citations

Induction of the Unspecific Microsomal Hydroxylase in the Human Liver

2015 • 75 citations

MECHANISM OF HEPATIC DRUG OXIDATION AND ITS RELATIONSHIP TO INDIVIDUAL DIFFERENCES IN RATES OF OXIDATION IN MAN*

1971 • 66 citations

Studies on the Metabolism of Ethynylestradiolin vitroandin vivo: The Significance of 2-Hydroxylation and the Formation of Polar Products

1973 • 65 citations

Cytochromes P‐450 and bs in human liver microsomes

1969 • 60 citations

Metabolism of radioactive 17α-ethynylestradiol by women

1970 • 59 citations

[The simultaneous use of rifampicin and other antitubercular agents with oral contraceptives].

1971 • 57 citations

PLASMA LEVELS OF ETHYNYLOESTRADIOL AFTER ADMINISTRATION OF ETHYNYLOESTRADIOL OR MESTRANOL TO HUMAN SUBJECTS

1973 • 51 citations

Oxidative drug metabolism in human liver microsomes.

1971 • 51 citations

Fate of Ingested Radiolabeled Ethynylestradiol and Its 3-Cyclopentyl Ether in Patients with Bile Fistulas

1969 • 50 citations

Pharmacology and the Future of Man

1974 • 48 citations

Einfluß von Tuberkulostatika auf die Pharmakokinetik des Digitoxins

1974 • 48 citations

RIFAMPICIN AND DRUG METABOLISM

1974 • 48 citations

Metabolic Study and Controlled Clinical Trials of Rifampin

1972 • 46 citations

Pharmacokinetics of mestranol in man in relation to its oestrogenic activity

1974 • 38 citations

Die aktivität der N- und O-demethylase in der leber des menschen

1970 • 33 citations

[Rimactan (rifampicin) and anticoagulant therapy].

1970 • 32 citations

Pathway and Stereochemistry of the Formation of Estriols in Man^*

1966 • 29 citations

Metabolism of 17α-Ethynyl-[4-¹⁴C]oestradiol and [4-¹⁴C]Mestranol in Rat Liver Slices and Interaction between 17α-Ethynyl-2-hydroxyoestradiol and Adrenalin

1973 • 27 citations

Die demethylierung von aminophenazon und codein in der leber des menschen

1970 • 26 citations

RIFAMPICIN AND ORAL CONTRACEPTION

1974 • 22 citations

Ring A Oxidation of 17α-Ethynylestradiol in Man

1974 • 18 citations

Micromethod for the preparation of a microsomal fraction from rat and human liver by differential sedimentation

1975 • 17 citations

Metabolism and mechanism of action of estrogens

1967 • 14 citations

Metabolism of 2-hydroxy[4-14C]estradiol by rat liver microsomes

1974 • 9 citations

Halbwertszeit von [4-14C]Östradiol-17ß in vivo sowie Stoffwechsel von [4-14C]Östron und [4-14C]Östriol in vitro bei Lebergesunden und bei Patienten mit Lebercirrhose

1973 • 8 citations

METABOLISM OF EHTYNYLOESTRADIOL AND MESTRANOL IN MAN AND INTERACTION BETWEEN 2-HYDROXY-ETHYNYLOESTRADIOL AND EPINEPHRINE

1974 • 7 citations

[Increased hydroxylation of estrogens in humans after administration of drugs. Demonstration by HTO analysis of body water].

1970 • 7 citations

4B. Steroid catabolism: Estrogens 103. The metabolism of ethynyl estradiol in women

1974 • 2 citations