Rapid reversal of alpha 2‐adrenoceptor agonist effects by atipamezole in human volunteers.

Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist

1988 • 676 citations

Reduced Narcotic Requirement by Clonidine with Improved Hemodynamic and Adrenergic Stability in Patients Undergoing Coronary Bypass Surgery

1987 • 455 citations

Anesthesia and hypertension: the effect of clonidine on perioperative hemodynamics and isoflurane requirements.

1987 • 313 citations

Pharmacological profiles of medetomidine and its antagonist, atipamezole.

1989 • 290 citations

Dexmedetomidine, an α2-Adrenoceptor Agonist, Reduces Anesthetic Requirements for Patients Undergoing Minor Gynecologic Surgery

1990 • 270 citations

Critical flicker frequency (CFF) and psychotropic drugs in normal human subjects?A review

1976 • 266 citations

Anesthesia and Hypertension

1987 • 261 citations

Effects of dexmedetomidine, a selective α2-adrenoceptor agonist, on hemodynamic control mechanisms

1989 • 238 citations

Reduction in Halothane Anesthetic Requirement by Clonidine, an Alpha-Adrenergic Agonist

1982 • 183 citations

Highly selective and specific antagonism of central and peripheral alpha 2-adrenoceptors by atipamezole.

1989 • 180 citations

Anesthetic and Hemodynamic Effects of the Stereoisomers of Medetomidine, an ??2-Adrenergic Agonist, in Halothane-Anesthetized Dogs

1988 • 145 citations

EVIDENCE FOR MEDETOMIDINE AS A SELECTIVE AND POTENT AGONIST α₂‐ADRENORECEPTORS

1986 • 145 citations

Hypokalaemia and other non‐bronchial effects of inhaled fenoterol and salbutamol: a placebo‐controlled dose‐response study in healthy volunteers.

1987 • 127 citations

Behavioural and neurochemical effects of antipamezole, a novel α2-adrenoceptor antagonist

1988 • 112 citations

Cardiovascular actions of medetomidine and their reversal by atipamezole.

1989 • 99 citations

Sedative and cardiovascular effects of medetomidine, a novel selective alpha 2‐adrenoceptor agonist, in healthy volunteers.

1987 • 89 citations

The Potentiation of Halothane Anaesthesia by Clonidine

1979 • 82 citations

Behavioural and neurochemical effects of atipamezole, a novel α2-adreneceptor antagonist

1988 • 75 citations

The use of medetomidine, medetomidine-ketamine combinations and atipamezole at Helsinki Zoo--a review of 240 cases.

1989 • 66 citations

Pharmacological effects and pharmacokinetics of atipamezole, a novel alpha 2‐adrenoceptor antagonist‐a randomized, double‐blind cross‐over study in healthy male volunteers.

1990 • 52 citations

Effects of acute administration of medetomidine on the behaviour, temperature and turnover rates of brain biogenic amines in rodents and reversal of these effects by atipamezole.

1989 • 44 citations

The analysis of repeated measures designs in medical research

1984 • 33 citations

Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine.

1989 • 27 citations

Assessment of MK-912, an α2-adrenoceptor antagonist, with use of intravenous clonidine

1989 • 16 citations

DEXMEDETOMIDINE MAY REDUCE ISOFLURANE REQUIREMENTS DURING ABDOMINAL HYSTERECTOMY

1990 • 6 citations

Deleted Work

1955 • 0 citations