Selective versus Total Insulin Resistance: A Pathogenic Paradox

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

2002 • 4,142 citations

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

2002 • 3,652 citations

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

2000 • 1,213 citations

Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications

1995 • 1,026 citations

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.

1994 • 813 citations

Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice

2000 • 805 citations

FROM MICE TO MEN: Insights into the Insulin Resistance Syndromes

2005 • 699 citations

What if Minkowski Had Been Ageusic? An Alternative Angle on Diabetes

1992 • 664 citations

Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis

2008 • 431 citations

Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

2006 • 414 citations

SREBP-1c Transcription Factor and Lipid Homeostasis: Clinical Perspective

2007 • 369 citations

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

2000 • 220 citations

Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice

2000 • 166 citations