Inhibition of biogenic amines uptake by imipramine, desipramine, 2 OH-imipramine and 2 OH-desipramine in rat brain

The determination of enzyme inhibitor constants

1953 • 4,050 citations

Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

1969 • 645 citations

Inhibition of Uptake of Tritiated-noradrenaline in the Intact Rat Brain by Imipramine and Structurally Related Compounds

1964 • 506 citations

Effects of some antidepressant drugs on the depletion of intraneuronal brain catecholamine stores caused by 4,α-dimethyl-meta-tyramine

1969 • 417 citations

Catecholamine uptake by synaptosomes from rat brain. Structure-activity relationships of drugs with differential effects on dopamine and norepinephrine neurons.

1971 • 283 citations

Uptake inhibition of biogenic amines by newer antidepressant drugs: Relevance to the dopamine hypothesis of depression

1977 • 264 citations

Tricyclic Antidepressant Agents. I. Comparison of the Inhibition of the Uptake of ³H‐Noradrenaline and ¹⁴C‐5‐Hydroxytryptamine in Slices and Crude Synaptosome Preparations of the Midbrain‐Hypothalamus Region of the Rat Brain

1975 • 198 citations

Biogenic Amines and Affective Disorders

1974 • 112 citations

Quantitative studies of norepinephrine uptake by synaptosomes

1968 • 110 citations

Effects of several tricyclic antidepressants on the hemodynamics and myocardial contractility of the anesthetized dogs

1977 • 99 citations

Decreased turnover in central 5-HT nerve terminals induced by antidepressant drugs of the imipramine type

1969 • 89 citations

Metabolism of tricyclic antidepressants. A review.

1974 • 66 citations

Distribution of protein-bound N-acetylneuraminic acid in subcellular particulate fractions prepared from rat whole brain

1969 • 66 citations

Drug Treatment of Mental Disorders

1976 • 39 citations

Antiarrhythmic effects of tricyclic antidepressant drugs in ouabain-induced arrhythmias in the dog.

1978 • 35 citations

THE PSYCHOBIOLOGY OF DEPRESSION

1976 • 17 citations

BINDING OF H3-IMIPRAMINE, H3-DIMETACRINE AND S35-CHLORPROMAZINE TO SYNAPTOSOMES

1978 • 6 citations