Polyamines mediate the reversible opening of the blood-brain barrier by the intracarotid infusion of hyperosmolal mannitol

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

POLYAMINES

1984 • 2,996 citations

FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE

1967 • 2,534 citations

Recent advances in the biochemistry of polyamines in eukaryotes

1986 • 1,587 citations

Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs

1978 • 998 citations

Blood-Brain Barrier in Physiology and Medicine

1976 • 888 citations

Experimental models of epilepsy

1973 • 526 citations

The Relationship Between Edema, Blood-Brain-Barrier and Tissue Elements in a Local Brain Injury

1958 • 390 citations

Testing of a hypothesis for osmotic opening of the blood-brain barrier

1972 • 366 citations

Osmotic opening of tight junctions in cerebral endothelium

1973 • 327 citations

Polyamines regulate calcium fluxes in a rapid plasma membrane response

1983 • 225 citations

The blood-brain barrier to horseradish peroxidase under normal and experimental conditions

1977 • 177 citations

Blood‐Brain Barrier in Physiology and Medicine

1977 • 166 citations

Reversible Osmotic Blood-Brain Barrier Disruption in Humans

1980 • 163 citations

Local cerebral glucose utilization in thermally traumatized rat brain

1981 • 114 citations

Osmotic opening of the blood‐brain barrier and local cerebral glucose utilization

1979 • 109 citations

Polyamines appear to be second messengers in mediating Ca2+ fluxes and neurotransmitter release in potassium-depolarized synaptosomes

1985 • 107 citations

Blood brain barrier breakdown in brain edema following cold injury is mediated by microvascular polyamines

1983 • 93 citations

Blood-brain barrier breakdown by cold injury. Polyamine signals mediate acute stimulation of endocytosis, vesicular transport, and microvillus formation in rat cerebral capillaries.

1986 • 85 citations

Opening of tight junctions in cerebral endothelium. I. Effect of hyperosmolar mannitol infused through the internal carotid artery

1979 • 85 citations

Blood–Brain Barrier Breakdown in Cold‐Injured Brain Is Linked to a Biphasic Stimulation of Ornithine Decarboxylase Activity and Polyamine Synthesis: Both Are Coordinately Inhibited by Verapamil, Dexamethasone, and Aspirin

1989 • 78 citations

Uptake of Amino Acids by Brain Microvessels Isolated from Rats after Portacaval Anastomosis

1981 • 72 citations

Measurement of the number of ornithine decarboxylase molecules in rat and mouse tissues under various physiological conditions by binding of radiolabelled α-difluoromethylornithine

1982 • 66 citations

Ornithine decarboxylase (EC 4.1.1.17) assay based upon the retention of putrescine by a strong cation-exchange paper

1981 • 63 citations

Ionic lanthanum passage across cerebral endothelium exposed to hyperosmotic arabinose

1983 • 60 citations

The mechanisms of blood-brain barrier impairment by hyperosmolar perfusion

1982 • 56 citations

Induction of pinocytosis in cerebral vessels by acute hypertension and by hyperosmolar solutions

1980 • 55 citations

CT abnormalities and altered methotrexate clearance in children with CNS leukemia

1984 • 50 citations

Polyamines and Ca²⁺ Mediate Hyperosmolal Opening of the Blood‐Brain Barrier: In Vitro Studies in Isolated Rat Cerebral Capillaries

1989 • 35 citations

Purification of mouse brain ornithine decarboxylase reveals its presence as an inactive complex with antizyme

1986 • 24 citations

Hyperosmotic Urea Reversibly Opens the Tight Junctions Between Brain Capillary Endothelial Cells in Cell Culture

1987 • 23 citations

Altered cerebral glucose utilization following blood-brain barrier opening by hypertonicity or hypertension

1981 • 19 citations

Formation of a barrier by brain microvessel endothelial cells in culture.

1987 • 18 citations

Polyamines mediate uncontrolled calcium entry and cell damage in rat heart in the calcium paradox.

1987 • 18 citations

Aspects of the Blood-Brain Barrier in Brain Edema

1969 • 15 citations