Drug-induced experimental lipidosis in the nervous system

Lysosomes in biology and pathology

1977 • 2,068 citations

Lysosomotropic agents

1974 • 1,887 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

Visual cells and the concept of renewal.

1976 • 484 citations

Lipidosis induced by amphiphilic cationic drugs

1978 • 353 citations

LYSOSOMES IN THE RAT SCIATIC NERVE FOLLOWING CRUSH

1965 • 321 citations

Drug-Induced Phospholipidoses

1975 • 286 citations

II. ULTRASTRUCTURE OF THE CEREBRUM*

1963 • 276 citations

Lamellar and hexagonal lipid phases visualized by freeze-etching

1970 • 262 citations

The origin and fate of secretory packages, especially synaptic vesicles

1977 • 178 citations

Degeneration and Regeneration of Neurosecretory Systems

1973 • 149 citations

NOTES ON SYNAPTIC VESICLES AND RELATED STRUCTURES, ENDOPLASMIC RETICULUM, LYSOSOMES AND PEROXISOMES IN NERVOUS TISSUE AND THE ADRENAL MEDULLA

1973 • 142 citations

The Pathology of Chloroquine Retinopathy

1964 • 142 citations

Structural studies of the associations between biological membrane components

1975 • 136 citations

EXPERIMENTAL CHLOROQUINE MYOPATHY

1970 • 128 citations

NERVOUS SYSTEM IN POMPEʼS DISEASE

1971 • 121 citations

Histopathology of Chloroquine Retinal Toxicity

1964 • 116 citations

Interactions of divalent cations or basic proteins with phosphatidylethanolamine vesicles

1977 • 97 citations

Cytochemical studies of protein transport in the nervous system

1971 • 90 citations

Neuropathological Conditions Related to Neuroaxonal Dystrophy

1971 • 86 citations

The ultrastructure of rat lung changes induced by an anorectic drug (Chlorphentermine)

1972 • 78 citations

Irreversible lysosomal damage induced by chloroquine in the retinae of pigmented and albino rats

1970 • 76 citations

Lysosomal alterations in cultured macrophages exposed to anorexigenic and psychotropic drugs.

1976 • 70 citations

AN ULTRASTRUCTURAL AND BIOCHEMICAL STUDY OF THE EFFECTS OF THREE INHIBITORS OF CHOLESTEROL BIOSYNTHESIS UPON MURINE ADRENAL GLAND AND TESTIS

1969 • 69 citations

Differences in the retinotoxic action of chloroquine and phenothiazine derivatives

1970 • 66 citations

Lipid storage diseases. Enzymatic defects and clinical implications

1972 • 56 citations

An ultrastructural study of axonal changes following constriction of postganglionic branches of the superio cervical ganglion in the rat

1973 • 54 citations

Drug-induced phospholipidosis

1975 • 51 citations

Study of chloroquine toxicity and a drug-induced cerebrospinal lipodystrophy in swine.

1968 • 49 citations

Lipidosis-like alterations in spinal cord and cerebellar cortex of rats treated with chlorphentermine or tricylic antidepressants

1974 • 49 citations

Experimentelle Sch�digungen von Nervensystem und Muskulatur durch Chlorochin: Modelle verschiedenartiger Speicherdystrophien

1974 • 48 citations

Amiodarone-induced lipidosis-like alterations in ocular tissues of rats

1978 • 45 citations

Perhexiline neuropathy: A clinicopathological study

1978 • 44 citations

Drug-induced retinal lipidosis: Differential susceptibilities of pigment epithelium and neuroretina toward several amphiphilic cationic drugs

1978 • 43 citations

Ultrastructural study of neuronal cytoplasmic inclusions produced by hypocholesterolemic Drug, AY 9944

1973 • 40 citations

Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs

1979 • 39 citations

Lipidosis-like ultrastructural alterations in rat lymph nodes after treatment with tricyclic antidepressants or neuroleptics

1974 • 38 citations

THE RESPONSE OF LYSOSOMES IN CULTURED NEURONS TO CHLORPROMAZINE

1970 • 37 citations

Etude en microscopie �lectronique des l�sions nerveuses, musculaires et cutan�es d�termin�es par le mal�ate de perhexiline

1977 • 35 citations

Current trends in sphingolipidoses and allied disorders

1977 • 33 citations

A Preliminary Study of the Effect of Chloroquine on the Rat Retina

1970 • 33 citations

Changes in brain hydrolytic enzyme activities in rats treated with cholesterol biosynthesis inhibitor, AY9944

1975 • 32 citations

An ultrastructural study of opaque cytoplasmic inclusions induced by triparanol treatment

1967 • 32 citations

Drug-Induced Foam Cell Reactions in Rats, II. Chemical Analysis of Lipids Stored in Lungs and Foam Cells after Treatment with Chlorphentermine, 5-[p-(Fluoren-9-ylidenemethyl)phenyl]-2-piperidineethanol (RMI 10.393) and 1-Chloramitriptyline

1975 • 31 citations

Perhexiline induces generalized lipidosis in rats

1978 • 29 citations

Effect of AY-9944, a cholesterol biosynthesis inhibitor, on peripheral nerve myelination.

1970 • 28 citations

The Fine Structure of Neocortical Synapses in Infantile Amaurotic Idiocy

1968 • 28 citations

Studies on Drug-Induced Lipidosis

1977 • 27 citations

Autophagy of Secretory Granules in the Rat Neurohypophysis

1973 • 26 citations

Effects of triparanol and 20,25-diazacholesterol in CNS of rat: Morphological and biochemical studies

1974 • 26 citations

Retinal lipidosis in albino rats treated with chlorphentermine and with tricyclic antidepressants

1976 • 26 citations

T-Lymphocyte depletion and lesions of choroid plexus and kidney induced by tertiary amines in rats

1977 • 25 citations

UV-induced changes in lysosomes tagged with quinacrine

1966 • 25 citations

Laboratory Studies of the 4-Amino-quinoline Antimalarials: I. Some Biochemical Characteristics of Chloroquine, Hydroxychloroquine, and SN-7718.

1961 • 25 citations

Ocular Changes in Swine Associated with Chloroquine Toxicity

1969 • 24 citations

Effects of cholesterol synthesis inhibitors on the nervous system. A light and electron microscopic study.

1968 • 23 citations

Differential effects of chloroquine and of several other amphiphilic cationic drugs upon rat choroid plexus

1979 • 22 citations

Some Findings on the Fine Structure of the Neurohypophysis in Dehydrated and Pitressin-Treated Mice

1975 • 21 citations

Morphological changes in CNS of rats treated with perhexiline maleate (Pexid)

1978 • 20 citations

Morphological and biochemical changes in the liver of various species in experimental phospholipidosis after diethylaminoethoxyhexestrol treatment

1975 • 20 citations

Lipidosis-like alterations in dorsal root ganglion cells of rats treated with tricyclic antidepressants

1974 • 16 citations

Niemann-Pick disease-like inclusions caused by a hypocholesteremic agent.

1976 • 16 citations

Lysosomal Bis(monoacylglycero)phosphate of Rat Liver, its Induction by Chloroquine and its Structure

1978 • 16 citations

Lipidosis-like alterations in hypothalamic neurosecretory cells of rats treated with chlorphentermine or iprindole

1974 • 15 citations

Alterations in the neurohypophysis of rats treated with chlorphentermine or tricyclic antidepressants

1976 • 14 citations

Increased lysosomal enzyme activities in tissues of rats suffering from chlorphentermine induced lipidosis

1979 • 13 citations

Myelin degeneration in sciatic nerve of rats treated with hypocholesteremic drug AY9944.

1972 • 12 citations

A quantitative electron microscopic analysis of myelination in the optic nerve of suckling rats treated with an inhibitor of cholesterol biosynthesis

1973 • 12 citations

Axonal and cellular alterations in the inner ear of rats treated with chlorphentermine or iprindole

1977 • 10 citations

Alterations in peripheral nerves of rats treated with chlorphentermine or with iprindole

1976 • 9 citations

Tissue distribution of chloroquine in rats in the course of long-term application.

1972 • 8 citations

Lipidose des Nervensystems nach Chlorphentermin-Applikation

1974 • 8 citations

Myopathy in rats treated with chlorphentermine or iprindole

1976 • 7 citations

Neuropathies périphériques au maléate de perhexiline.

1977 • 7 citations

Changes caused by chloroquine in cultured nervous tissues of the rat

1975 • 7 citations

Ultrastructure and Biochemical Studies of Rat CNS and Viscera after Subcutaneous Injection of Chlorphentermine

1976 • 4 citations

The Effects of Nortriptyline and Mesoridazine on Neurons and Gliain Vitro

1977 • 3 citations

Alterations of Lysosomes by Amphiphilic Drugs

1978 • 2 citations