TRANCE/RANKL Knockout Mice Are Protected from Bone Erosion in a Serum Transfer Model of Arthritis

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

1998 • 5,369 citations

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

1997 • 5,058 citations

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1998 • 4,184 citations

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 • 3,340 citations

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1997 • 2,257 citations

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

1999 • 1,832 citations

Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesisin Vitro¹

1998 • 1,211 citations

The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption

2000 • 1,169 citations

Modulation of Osteoclast Differentiation

1992 • 1,014 citations

A microtomographic system for the nondestructive evaluation of bone architecture

1996 • 885 citations

Organ-Specific Disease Provoked by Systemic Autoimmunity

1996 • 880 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor

2000 • 811 citations

From Systemic T Cell Self-Reactivity to Organ-Specific Autoimmune Disease via Immunoglobulins

1999 • 689 citations

Morphometric Analysis of Human Bone Biopsies: A Quantitative Structural Comparison of Histological Sections and Micro-Computed Tomography

1998 • 646 citations

Arthritis Provoked by Linked T and B Cell Recognition of a Glycolytic Enzyme

1999 • 620 citations

Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis

2000 • 600 citations

Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis.

1998 • 514 citations

Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis.

2000 • 456 citations

Osteotropic Agents Regulate the Expression of Osteoclast Differentiation Factor and Osteoprotegerin in Osteoblastic Stromal Cells

1998 • 444 citations

Activated T Lymphocytes Support Osteoclast Formation in Vitro

1999 • 408 citations

Trance, a Tumor Necrosis Factor Family Member, Enhances the Longevity and Adjuvant Properties of Dendritic Cells in Vivo

2000 • 335 citations

Osteoprotegerin Production by Human Osteoblast Lineage Cells Is Stimulated by Vitamin D, Bone Morphogenetic Protein-2, and Cytokines

1998 • 312 citations

Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene

2000 • 297 citations

Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint

1984 • 286 citations

A novel molecular mechanism modulating osteoclast differentiation and function

1999 • 267 citations

Regulation of Peripheral Lymph Node Genesis by the Tumor Necrosis Factor Family Member Trance

2000 • 262 citations

Initiation of Osteoclast Bone Resorption by Interstitial Collagenase

1997 • 250 citations

Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone

1994 • 249 citations

Increased bone mass with pamidronate treatment in rheumatoid arthritis. Results of a three‐year randomized, double‐blind trial

1996 • 226 citations

Micro-tomographic imaging for the nondestructive evaluation of trabecular bone architecture.

1997 • 196 citations

Expression of osteoclast differentiation factor at sites of bone erosion in collagen-induced arthritis

2000 • 193 citations

Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: Comparison of efficacy in animal models with human clinical data

1999 • 155 citations

Calcitonin Receptors as Markers for Osteoclastic Differentiation: Correlation between Generation of Bone-Resorptive Cells and Cells that Express Calcitonin Receptors in Mouse Bone Marrow Cultures*

1989 • 152 citations

Genetic Influences on the End-Stage Effector Phase of Arthritis

2001 • 149 citations

Cysteine proteinase cathepsin K mRNA is expressed in synovium of patients with rheumatoid arthritis and is detected at sites of synovial bone destruction.

1998 • 149 citations

A role for osteocalcin in osteoclast differentiation

1991 • 148 citations

Quantification of Periapical Bone Destruction in Mice by Micro-computed Tomography

2000 • 145 citations

Failure of cells of the mononuclear phagocyte series to resorb bone

1984 • 138 citations

Generation of Osteoclastic Function in Mouse Bone Marrow Cultures: Multinuclearity and Tartrate- Resistant Acid Phosphatase Are Unreliable Markers for Osteoclastic Differentiation*

1989 • 124 citations

Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis

2001 • 117 citations

Expression of the calcitonin receptor in bone marrow cell cultures and in bone: a specific marker of the differentiated osteoclast that is regulated by calcitonin.

1995 • 113 citations

Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors

1999 • 107 citations

Osteoclast-like cells in murine collagen induced arthritis.

1998 • 88 citations

NE-58095: a diphosphonate which prevents bone erosion and preserves joint architecture in experimental arthritis.

1989 • 70 citations

Gene expression during osteoclast-like cell formation induced by antifusion regulatory protein-1/CD98/4F2 monoclonal antibodies (MAbs): c-src is selectively induced by anti-FRP-1 MAb

1999 • 65 citations

The erosive front: a topographic study of the junction between the pannus and the subchondral plate in the macerated rheumatoid metacarpal head.

1988 • 63 citations

Sequential Expression of Phenotype Markers for Osteoclasts during Differentiation of Precursors for Multinucleated Cells Formed in Long Term Human Marrow Cultures*

1990 • 63 citations

Induction of abundant osteoclast-like multinucleated giant cells in adjuvant arthritic rats with accompanying disordered high bone turnover.

1998 • 54 citations

Intranasal calcitonin for the prevention of bone erosion and bone loss in rheumatoid arthritis.

1992 • 39 citations