Specific interaction of HTLV tax protein and a human type IV neuronal intermediate filament protein

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

Neurofilament gene expression: a major determinant of axonal caliber.

1987 • 705 citations

Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease

1990 • 603 citations

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1993 • 550 citations

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis

1993 • 549 citations

The tat Gene of Human T-Lymphotropic Virus Type 1 Induces Mesenchymal Tumors in Transgenic Mice

1987 • 522 citations

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

1995 • 464 citations

Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction.

1992 • 318 citations

HTLV-I Tax Protein Stimulation of DNA Binding of bZIP Proteins by Enhancing Dimerization

1993 • 312 citations

Mechanism of action of regulatory proteins encoded by complex retroviruses

1992 • 299 citations

Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein

1994 • 284 citations

A Transgenic Mouse Model for Human Neurofibromatosis

1987 • 278 citations

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

1993 • 270 citations

Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit.

1990 • 173 citations

Detection of human T‐lymphotropic virus type I (HTLV‐I) tax RNA in the central nervous system of HTLV‐I–associated myelopathy/tropical spastic paraparesis patients by in situ hybridization

1995 • 170 citations

Increased HTLV‐I proviral DNA in HTLV‐I–associated myelopathy: A quantitative polymerase chain reaction study

1991 • 153 citations

Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins

1992 • 135 citations

Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax

1995 • 131 citations

A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.

1993 • 129 citations

Characterization of dominant and recessive assembly-defective mutations in mouse neurofilament NF-M.

1990 • 116 citations

Human T‐lymphotropic virus type I‐associated myelopathy and tax gene expression in CD4⁺ T lymphocytes

1996 • 102 citations

HTLV-I proviral DNA amount correlates with infiltrating CD4+ lymphocytes in the spinal cord from patients with HTLV-I-associated myelopathy

1994 • 96 citations

Functional interaction of the HTLV-1 transactivator Tax with activating transcription factor-4 (ATF4)

1997 • 81 citations

Induction of nuclear NF-kappa B DNA binding activity after exposure of lymphoid cells to soluble tax1 protein.

1990 • 76 citations

Immunologic Analysis of a Spinal Cord–Biopsy Specimen from a Patient with Human T-Cell Lymphotropic Virus Type I–Associated Neurologic Disease

1997 • 75 citations

Tax1 induction of the HTLV-I 21 bp enhancer requires cooperation between two cellular DNA-binding proteins.

1990 • 74 citations

Expression of the 3′ Terminal Region of Human T-Cell Leukemia Viruses

1984 • 73 citations

Direct interaction of CREB protein with 21 bp Tax-response elements of HTLV-ILTR.

1992 • 69 citations

Nucleotide sequence analysis of a provirus derived from HTLV-1-associated myelopathy (HAM).

1988 • 64 citations

Extracellular human T‐cell lymphotropic virus type I tax protein induces cytokine production in adult human microglial cells

1994 • 61 citations

Soluble HTLV-I Tax1 protein stimulates proliferation of human peripheral blood lymphocytes.

1991 • 58 citations

Genetic Characterization of Transactivation of the Human T-Cell Leukemia Virus Type 1 Promoter: Binding of Tax to Tax-Responsive Element 1 Is Mediated by the Cyclic AMP-Responsive Members of the CREB/ATF Family of Transcription Factors

1996 • 57 citations

Effects of truncated neurofilament proteins on the endogenous intermediate filaments in transfected fibroblasts

1991 • 50 citations

Activation of interleukin-2 receptor alpha expression by extracellular HTLV-I Tax1 protein: a potential role in HTLV-I pathogenesis.

1992 • 46 citations

Retrovirus From Human T-Cell Leukemia Virus Type I-Associated Myelopathy Is the Same Strain as a Prototype Human T-Cell Leukemia Virus Type I

1990 • 45 citations

Tax mutation associated with tropical spastic paraparesis/human T-cell leukemia virus type I-associated myelopathy

1995 • 45 citations

Cloning and developmental expression of human 66 kd neurofilament protein

1995 • 24 citations

Host-HTLV Type I Interaction at the Molecular Level

1994 • 16 citations