Development of Histocompatible Primate‐Induced Pluripotent Stem Cells for Neural Transplantation

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2001 • 156,143 citations

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

2007 • 19,034 citations

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

2007 • 9,934 citations

Estimation of nuclear population from microtome sections

1946 • 4,378 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Reprogramming of human somatic cells to pluripotency with defined factors

2007 • 2,846 citations

Transplantation of Embryonic Dopamine Neurons for Severe Parkinson's Disease

2001 • 2,290 citations

Disease-Specific Induced Pluripotent Stem Cells

2008 • 2,123 citations

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

2009 • 1,541 citations

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

2008 • 1,194 citations

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

2002 • 1,179 citations

TRANSPLANTATION OF EMBRYONIC DOPAMINE NEURONS FOR SEVERE PARKINSON'S DISEASE

2001 • 1,013 citations

Derivation of midbrain dopamine neurons from human embryonic stem cells

2004 • 981 citations

Immunologically Privileged Sites

1978 • 815 citations

What is immune privilege (not)?

2006 • 708 citations

Characterization of the expression of MHC proteins in human embryonic stem cells

2002 • 659 citations

Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model

2005 • 478 citations

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

2010 • 464 citations

Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease

2005 • 421 citations

Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

2005 • 362 citations

Human Embryonic Stem Cells Possess Immune‐Privileged Properties

2004 • 359 citations

Foxa1andFoxa2regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner

2007 • 271 citations

Enhanced Yield of Neuroepithelial Precursors and Midbrain-Like Dopaminergic Neurons from Human Embryonic Stem Cells Using the Bone Morphogenic Protein Antagonist Noggin

2006 • 252 citations

CD15, CD24, and CD29 Define a Surface Biomarker Code for Neural Lineage Differentiation of Stem Cells

2009 • 224 citations

Immune problems in central nervous system cell therapy

2004 • 189 citations

Xenotransplantation of Porcine Fetal Ventral Mesencephalon in a Rat Model of Parkinson's Disease: Functional Recovery and Graft Morphology

1996 • 171 citations

Simian Immunodeficiency Virus SIVmac239 Infection of Major Histocompatibility Complex-Identical Cynomolgus Macaques from Mauritius

2006 • 158 citations

Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques

2007 • 128 citations

A novel mode of immunoprotection of neural xenotransplants: Masking of donor major histocompatibility complex class I enhances transplant survival in the central nervous system

1995 • 112 citations

Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells

2010 • 99 citations

Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism

1992 • 99 citations

Mapping Dopamine Function in Primates Using Pharmacologic Magnetic Resonance Imaging

2004 • 90 citations

Non‐human primates: essential partners in biomedical research

2001 • 90 citations

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease

2008 • 82 citations

Sequential Intracerebral Transplantation of Allogeneic and Syngeneic Fetal Dopamine-Rich Neuronal Tissue in Adult Rats: Will the First Graft be Rejected?

1993 • 71 citations

The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviors

2008 • 62 citations

MHC class I characterization of Indonesian cynomolgus macaques

2008 • 60 citations

Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA-lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons

1997 • 58 citations

Survival and immunogenicity of dissociated allogeneic fetal neural dopamine-rich grafts when implanted into the brains of adult mice

1989 • 54 citations

Lack of functional relevance of isolated cell damage in transplants of Parkinson’s disease patients

2009 • 51 citations

MHC haplotype frequencies in a UK breeding colony of Mauritian cynomolgus macaques mirror those found in a distinct population from the same geographic origin

2008 • 50 citations

Immunological Barriers to Embryonic Stem Cell-Derived Therapies

2008 • 48 citations

Allograft inflammatory factor-1 and its immune regulation

2007 • 47 citations

The blood–brain barrier is intact after levodopa-induced dyskinesias in parkinsonian primates—Evidence from in vivo neuroimaging studies

2009 • 34 citations

Intracerebral cytokine profiles in adult rats grafted with neural tissue of different immunological disparity

2004 • 28 citations