Photodynamic Therapy in the Treatment of Cancer

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

New trends in photobiology

1992 • 1,194 citations

Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer.

1996 • 1,120 citations

THE PHOTODEGRADATION OF PORPHYRINS IN CELLS CAN BE USED TO ESTIMATE THE LIFETIME OF SINGLET OXYGEN

1991 • 990 citations

The Use of a Derivative of Hematoporphyrin in Tumor Detection<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>

1961 • 634 citations

5‐Aminolevulinic Acid‐Based Photodynamic Therapy: Principles and Experimental Research

1997 • 630 citations

Photodynamic therapy of non-melanoma malignant tumours of the skin using topical δ-amino levulinic acid sensitization and laser irradiation

1994 • 432 citations

Oxygen Consumption and Diffusion Effects in Photodynamic Therapy

1991 • 402 citations

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system

1997 • 388 citations

Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolaevulinic acid induced protoporphyrin IX--a pilot study.

1995 • 365 citations

Superficial photodynamic therapy with topical 5-aminolaevulinic acid for superficial primary and secondary skin cancer

1994 • 365 citations

Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid

1993 • 356 citations

The physics of photodynamic therapy

1986 • 344 citations

Photodynamic therapy with porfimer sodium versus thermal ablation therapy with Nd:YAG laser for palliation of esophageal cancer: a multicenter randomized trial

1995 • 336 citations

Mitochondrial photodamage and PDT-induced apoptosis

1998 • 329 citations

Photoimmunotherapy: treatment of animal tumors with tumor-specific monoclonal antibody-hematoporphyrin conjugates.

1983 • 311 citations

The mechanism of photodynamic inactivation of human cells in vitro in the presence of haematoporphyrin

1979 • 273 citations

Tumour photosensitizers: approaches to enhance the selectivity and efficiency of photodynamic therapy

1996 • 256 citations

Induction of Tumor Immunity by Photodynamic Therapy

1996 • 256 citations

Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI.

1996 • 209 citations

Photosensitization of malignant tumors

1986 • 180 citations

Photodynamic Therapy for the Treatment of Basal Cell Carcinoma

1992 • 177 citations

Photodynamic Therapy with Hematoporphyrin Derivative in the Treatment of Superficial Transitional-Cell Carcinoma of the Bladder

1987 • 174 citations

Evidence for low-density lipoprotein receptor-mediated uptake of benzoporphyrin derivative

1994 • 164 citations

New trends in photobiology

1991 • 161 citations

Phase I study of debulking surgery and photodynamic therapy for disseminated intraperitoneal tumors

1993 • 155 citations

Photodynamic Therapy for Early Stage Squamous Cell Carcinoma of the Lung

1997 • 141 citations

DNA single-strand breaks and sister chromatid exchanges induced by treatment with hematoporphyrin and light or by x-rays in human NHIK 3025 cells.

1980 • 133 citations

Biodistribution of tritiated benzoporphyrin derivative (3H-BPD-MA), a new potent photosensitizer, in normal and tumor-bearing mice

1990 • 129 citations

Photoradiation Therapy of Bladder Tumors

1983 • 114 citations

New trends in photobiology

1990 • 109 citations

Photodynamic therapy as adjuvant therapy in surgically treated pleural malignancies

1997 • 108 citations

ALUMINUM SULFONATED PHTHALOCYANINE DISTRIBUTION IN RODENT TUMORS OF THE COLON, BRAIN and PANCREAS

1987 • 106 citations

The Effect of Fluence Rate on Tumor and Normal Tissue Responses to Photodynamic Therapy

1998 • 106 citations

Effects of various photoradiation regimens on the antitumor efficacy of photodynamic therapy for R3230AC mammary carcinomas.

1990 • 105 citations

Comparison of mutagenicity and induction of sister chromatid exchange in Chinese hamster cells exposed to hematoporphyrin derivative photoradiation, ionizing radiation, or ultraviolet radiation.

1983 • 101 citations

Intrapleural photodynamic therapy: Results of a phase I trial

1994 • 101 citations

Hematoporphyrin photodynamic therapy: Is there truly a future in head and neck oncology? Reflections on a 5‐year experience

1991 • 97 citations

Effects of photodynamic therapy using mono-L-aspartyl chlorin e6 on vessel constriction, vessel leakage, and tumor response.

1994 • 92 citations

Hematoporphyrin Derivative and Laser Photoradiation in the Diagnosis and Treatment of Bladder Cancer

1983 • 87 citations

Influence of Fractionation and Fluence Rate in Photodynamic Therapy with Photofrin or mTHPC

1996 • 82 citations

Photodynamic Therapy for Barrett’s Esophagus

2009 • 81 citations

The effect of tissue and cellular pH on the selective biodistribution of porphyrin-type photochemotherapeutic agents: A volumetric titration study

1990 • 79 citations

Interstitial and transurethral photodynamic therapy of the canine prostate using meso-tetra-(m-hydroxyphenyl) chlorin

1996 • 79 citations

Photosensitizing efficacy of MTHPC‐PDT compared to Photofrin‐PDT in the RIF1 mouse tumour and normal skin

1995 • 67 citations

THE EFFECTS OF PHOTODYNAMIC THERAPY USING DIFFERENTLY SUBSTITUTED ZINC PHTHALOCYANINES ON VESSEL CONSTRICTION, VESSEL LEAKAGE AND TUMOR RESPONSE

1993 • 65 citations

The Effects of Thrombocytopenia on Vessel Stasis and Macromolecular Leakage after Photodynamic Therapy Using Photofrin

1997 • 65 citations

Effect of photodynamic therapy on the endothelium-dependent relaxation of isolated rat aortas.

1993 • 57 citations

The use of non-hypoxic cell sensitizers in radiobiology and radiotherapy

1986 • 57 citations

Photodynamic therapy for chest wall recurrence in breast cancer

1991 • 55 citations

Low density lipoprotein receptor pathway in the delivery of Photofrin: How much is it relevant for selective accumulation of the photosensitizer in tumors?

1992 • 54 citations

THE EFFECTS OF THROMBOXANE INHIBITORS ON THE MICROVASCULAR AND TUMOR RESPONSE TO PHOTODYNAMIC THERAPY

1993 • 53 citations

Laser Photodynamic Therapy for Bladder Cancer

1986 • 45 citations

Light dosimetry for photodynamic therapy in the esophagus

1997 • 42 citations

A controlled trial of Nd-YAG laser vs photodynamic therapy for advanced malignant bronchial obstruction

1993 • 41 citations

Photosensitization and split-dose recovery in cultured human urinary bladder carcinoma cells containing nonexchangeable hematoporphyrin derivative.

1985 • 40 citations

Photosensitizing effects of hematoporphyrin derivative and photofrin II on the plasma membrane enzymes 5'-nucleotidase, Na+K+-ATPase, and Mg2+-ATPase in R3230AC mammary adenocarcinomas.

1988 • 38 citations

Effect of axial ligation and delivery system on the tumour-localising and -photosensitising properties of Ge(IV)-octabutoxy-phthalocyanines

1995 • 32 citations

Photodynamic Membrane Damage of Hematoporphyrin Derivative-Treated Nhik 3025 Cells in Vitro

1981 • 27 citations

Photodosimetry of interstitial light delivery to solid tumors

1994 • 20 citations

Photobiological properties of hematoporphyrin diesters: Evaluation for possible application in photochemotherapy of cancer

1993 • 19 citations

<title>Clinical status of benzoporphyrin derivative</title>

1996 • 13 citations

Potentiation of chemotherapy cytotoxicity following iododeoxyuridine incorporation in Chinese hamster cells

1986 • 13 citations

Photoradiation therapy of bladder tumours.

1984 • 10 citations

The use of the laser in gynecology.

1983 • 1 citations