Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors

Applied logistic regression

1990 • 37,000 citations

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

p53: puzzle and paradigm.

1996 • 2,363 citations

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

1991 • 2,142 citations

Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype

1997 • 1,329 citations

Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.

1993 • 796 citations

Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support

1989 • 747 citations

The pathway to signal achievement

1993 • 563 citations

Identification of mismatch repair genes and their role in the development of cancer

1995 • 319 citations

Principles and Practice of Endocrinology and Metabolism

1996 • 278 citations

Microsatellite instability in human solid tumors

1998 • 243 citations

Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.

1991 • 210 citations

Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas

1995 • 171 citations

K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location

1994 • 137 citations

Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection

1991 • 134 citations

Dehydroepiandrosterone and Structural Analogs: A New Class of Cancer Chemopreventive Agents

1988 • 130 citations

TP53 and long-term prognosis in colorectal cancer: mutations in the L3 zinc-binding domain predict poor survival.

1998 • 126 citations

Gender and colorectal cancer

1993 • 112 citations

Microsatellite instability in human solid tumors

1997 • 88 citations

Ki-ras mutation modifies the protective effect of dietary monounsaturated fat and calcium on sporadic colorectal cancer.

1997 • 75 citations

C-KI-RAS activation and the biological behaviour of proximal and distal colonic adenocarcinomas

1996 • 75 citations

p53 and behaviour of colorectal cancer

1994 • 72 citations

Variables associated with the risk of colorectal adenomas in asymptomatic patients with a family history of colorectal cancer.

1995 • 67 citations

Genetic alterations within the retinoblastoma locus in colorectal carcinomas. Relation to DNA ploidy pattern studied by flow cytometric analysis

1991 • 61 citations

Inhibition of protein isoprenylation and p21ras membrane association by dehydroepiandrosterone in human colonic adenocarcinoma cells in vitro.

1991 • 53 citations

Frequency and spectrum of c-Ki-ras mutations in human sporadic colon carcinoma, carcinomas arising in ulcerative colitis, and pancreatic adenocarcinoma.

1991 • 45 citations

Environmental dietary factors in colorectal cancer some unresolved issues

1992 • 43 citations

K-ras mutations and HLA-DR expression in large bowel adenomas

1996 • 37 citations

History of childbearing and colorectal cancer risk in women aged less than 60: An analysis of Swedish routine registry data 1960–1984

1996 • 24 citations

History of childbearing and colorectal cancer risk in women aged less than 60: An analysis of Swedish routine registry data 1960–1984

1996 • 21 citations