HLA typing in the United Kingdom multiple sclerosis genome screen

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

1993 • 3,693 citations

Parametric and nonparametric linkage analysis: a unified multipoint approach.

1996 • 2,905 citations

The 1993–94 Généthon human genetic linkage map

1994 • 1,870 citations

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

A genome-wide search for human type 1 diabetes susceptibility genes

1994 • 1,294 citations

Complete multipoint sib-pair analysis of qualitative and quantitative traits.

1995 • 929 citations

A full genome search in multiple sclerosis

1996 • 666 citations

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex

1996 • 650 citations

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

1996 • 638 citations

HLA class II-associated genetic susceptibility in multiple sclerosis: A critical evaluation

1991 • 487 citations

HISTOCOMPATIBILITY DETERMINANTS IN MULTIPLE SCLEROSIS, WITH SPECIAL REFERENCE TO CLINICAL COURSE

1973 • 472 citations

The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation

1995 • 471 citations

Asymptotic properties of affected-sib-pair linkage analysis.

1993 • 378 citations

OCCURRENCE OF A MULTIPLE SCLEROSIS-LIKE ILLNESS IN WOMEN WHO HAVE A LEBER'S HEREDITARY OPTIC NEUROPATHY MITOCHONDRIAL DNA MUTATION

1992 • 373 citations

HL-A ANTIGENS AND MULTIPLE SCLEROSIS

1972 • 315 citations

Genomewide Scan of Multiple Sclerosis in Finnish Multiplex Families

1997 • 308 citations

Chromosome–specific microsatellite sets for fluorescence–based, semi–automated genome mapping

1994 • 304 citations

Nomenclature for Factors of the HLA System, 1995

1995 • 265 citations

Leber's hereditary optic neuropathy mitochondrial DNA mutations in multiple sclerosis

1994 • 146 citations

HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis

1991 • 140 citations

Genetic predisposition to multiple sclerosis as revealed by immunoprinting

1997 • 135 citations

B-LYMPHOCYTE ALLOANTIGENS ASSOCIATED WITH MULTIPLE SCLEROSIS

1976 • 128 citations

Identification of the HLA-DRB1∗04, -DRB1∗07, and -DRB1∗09 Alleles by PCR Amplification with sequence-specific primers (PCR-SSP) in 2 hours

1992 • 120 citations

Association of susceptibility to multiple sclerosis in Sweden with HLA class II DRB1 and DQB1 alleles

1994 • 119 citations

Clinical concordance in sibling pairs with multiple sclerosis

1996 • 81 citations

Mitochondrial DNA mutations in multiple sclerosis

1995 • 77 citations

Multiple sclerosis and the HLA-D region: linkage and association studies

1995 • 76 citations

No association of the 11778 rnitochondrial DNA mutation and multiple sclerosis in Japan

1995 • 45 citations

Tumour necrosis factor microsatellites show association with multiple sclerosis

1997 • 41 citations

HLA‐DQ polymorphisms do not explain HLA class II associations with multiple sclerosis in two Canadian patient groups

1993 • 23 citations