Effects of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate on newly synthesized proteins in mouse epidermis

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Biology of the Skin and Hair Growth

1966 • 610 citations

Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.

1975 • 504 citations

Keratin filaments of cultured human epidermal cells. Formation of intermolecular disulfide bonds during terminal differentiation.

1978 • 501 citations

Studies on the mechanism of skin tumor promotion: Evidence for several stages in promotion

1980 • 336 citations

The Proteins of the Mammalian Epidermis

1952 • 201 citations

Ultrastructural, histological, and biochemical alterations produced by 12-O-tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin tumor promotion.

1973 • 196 citations

Action of phorbol esters in cell culture: Mimicry of transformation, altered differentiation, and effects on cell membranes

1979 • 181 citations

Sequential Aspects of Chemical Carcinogenesis: Skin

1975 • 159 citations

Effects of phorbol and four diesters of phorbol on the incorporation of tritiated precursors into DNA, RNA, and protein in mouse epidermis.

1971 • 159 citations

Effects of phorbol-12,13-diesters on prostaglandin production and phospholipase activity in canine kidney (MDCK) cells

1977 • 155 citations

Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.

1979 • 135 citations

Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator.

1977 • 117 citations

The stimulation of phospholipid metabolism in mouse skin following phorbol ester treatment

1972 • 113 citations

Effect of tumor-promoting phorbol esters and of acetic acid on mechanisms controlling DNA synthesis and mitosis (Chalones) and on the biosynthesis of histidine-rich protein in mouse epidermis.

1974 • 112 citations

Prostaglandin E-mediated mitogenic stimulation of mouse epidermis in vivo by divalent cation ionophore A 23187 and by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.

1981 • 110 citations

Biochemical Evidence for Keratinization by Mouse Epidermal Cells in Culture

1978 • 97 citations

Stimulation of the phosphorylation of mouse epidermal histones by tumor-promoting agents.

1973 • 77 citations

The early stimulation of phospholipid metabolism by 12-0-tetradecanoyl-phorbol-13-acetate and its specificity for tumor promotion.

1973 • 76 citations

The effect of the phorbol ester tumor promoters on the basal and catecholamine-stimulated levels of cyclic adenosine 3':5'-monophosphate in mouse skin and epidermis in vivo.

1977 • 74 citations

Cell proliferation and promoting action in skin carcinogenesis.

1974 • 73 citations

Acetic Acid, a Potent Stimulator of Mouse Epidermal Macromolecular Synthesis and Hyperplasia but With Weak Tumor-Promoting Ability 2

1975 • 72 citations

Resolution of basic cellular proteins including histone variants by two-dimensional gel electrophoresis: Evaluation of lysine to arginine ratios and phosphorylation

1980 • 67 citations

Effects of phorbol ester tumor promoters on arachidonic acid metabolism in chick embryo fibroblasts.

1979 • 64 citations

The Synthesis Of Specific Proteins In Adult Mouse Epidermis During Phases Of Proliferation And Differentiation Induced By The Tumor Promoter Tpa, And In Basal And Differentiating Layers Of Neonatal Mouse Epidermis

1976 • 57 citations

Local vascular changes induced by the cocarcinogen, phorbol myristate acetate.

1970 • 52 citations

Ultrastructural and biochemical changes induced in mouse epidermis by a hyperplastic agent, ethylphenylpropiolate.

1973 • 50 citations

Proteins of Mammalian Epidermis*

1955 • 49 citations

Decrease of epidermal histidase activity by tumor-promoting phorbol esters.

1975 • 41 citations

Protein synthesis during fetal development of mouse epidermis

1977 • 41 citations

Croton oil- and benzo(a)pyrene-induced changes in cyclic adenosine 3':5'-monophosphate and cyclic guanosine 3':5'-monophosphate phosphodiesterase activities in mouse epidermis.

1976 • 26 citations

Histone phosphorylation and synthesis of DNA and RNA during phases of proliferation and differentiation induced in mouse epidermis by the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.

1977 • 21 citations

Epidermal ribosome accumulation during two-stage skin tumorigenesis.

1977 • 18 citations

Increased cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in the epidermis of phorbol ester-treated mouse skin and in papillomas.

1979 • 14 citations

Fluctuations in the production of specific cellular peptides during the growth of animal cells.

1978 • 11 citations