Back to search

Structural analysis of an HLA-B27 functional variant: identification of residues that contribute to the specificity of recognition by cytolytic T lymphocytes.

Data up to Jan 2025

Published1985
Citations34
References35

Total Citations Per Year

Abstract

References (35)

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

High Association of an HL-A Antigen, W27, with Ankylosing Spondylitis

1973 • 1,365 citations

THE SMALL SUBUNIT OF HL-A ANTIGENS IS ß2-MICROGLOBULIN

1973 • 362 citations

The structure of a mutant H–2 gene suggests that the generation of polymorphism in H–2 genes may occur by gene conversion-like events

1983 • 277 citations

Exon/intron organization and complete nucleotide sequence of an HLA gene.

1982 • 239 citations

Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens

1982 • 229 citations

Spontaneous H-2 mutants provide evidence that a copy mechanism analogous to gene conversion generates polymorphism in the major histocompatibility complex.

1983 • 188 citations

Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes.

1984 • 158 citations

Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region.

1976 • 127 citations

Comparison of the cloned H-2Kbm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences.

1983 • 120 citations

Structure of Class I Major Histocompatibility Antigens

1983 • 107 citations

Monoclonal antibody (B27M2) subdividing HLA-B27

1982 • 106 citations

Structure of crossreactive human histocompatibility antigens HLA-A28 and HLA-A2: possible implications for the generation of HLA polymorphism.

1982 • 106 citations

The HLA-AW24 gene: Sequence, surroundings and comparison with the HLA-A2 and HLA-A3 genes

1985 • 96 citations

Fine specificity of alloimmune cytotoxic T lymphocytes directed against H-2K. A study with Kb mutants.

1980 • 86 citations

Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire.

1980 • 84 citations

Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules

1980 • 80 citations

Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes: variants M7 and DR1

1982 • 75 citations

Definition of four HLA-A2 subtypes by CML typing and biochemical analysis

1983 • 73 citations

Intramolecular organization of Class I H-2 MHC antigens; localization of the alloantigenic determinants and the beta 2 m binding site to different regions of the H-2 Kb glycoprotein.

1983 • 70 citations

Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes. II. Variant DK1: evidence for a discrete CTL recognition region.

1983 • 67 citations

Regulation of the cytotoxic T lymphocyte response against Sendai virus analyzed with H-2 mutants.

1983 • 63 citations

Identification of several functional subgroups of HLA-B27 by restriction of the activity of antiviral T killer lymphocytes

1984 • 55 citations

Heterogeneity of HL-A Antigen Preparations Is Due to Variable Sialic Acid Content

1974 • 52 citations

Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T lymphocytes.

1984 • 49 citations

Primary structure of papain-solubilized human histocompatibility antigen HLA-B27

1985 • 47 citations

Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens: evidence for recognition of distinct self structures in conjunction with different foreign antigens.

1981 • 45 citations

Identification of human CML target. HLA-B locus (B12) antigen variants defined by CTL generated between B locus-identical (B12) responder-stimulator pairs.

1982 • 37 citations

H-2Kb mutations limit the CTL response to SV40 TASA.

1982 • 33 citations

An electrofocusing system for the analysis of proteins and their genetic variants

1978 • 29 citations

Two subgroups of HLA Bw44 defined by cell-mediated lympholysis that differ in Bw44 expression on platelets and in patterns of genetic linkage disequilibrium.

1982 • 26 citations

HLA-B27, A dominant restricting element in antiviral responses?

1984 • 25 citations

H-2 effects on cell-cell interactions in the response to single non-H-2 alloantigens. V. Effects of H-2Kb mutations on presentation of H-4 and H-3 alloantigens.

1982 • 22 citations

Cell-mediated lympholysis responses against autologous cells modified with haptenic sulfhydryl reagents. IV. Self-determinants recognized by wild-type anti-H-2Kb and H-2Db-restricted cytotoxic T cells specific for sulfhydryl and amino-reactive haptens are absent in certain H-2 mutant strains.

1982 • 16 citations

[52] Purification of human HLA-A and HLA-B class I histocompatibility antigens

1984 • 8 citations

Cited By (0)

No citing papers found in database

Structural analysis of an HLA-B27 functional variant: identification of residues that… (1985) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer