Mechanisms of loss of HLA class I expression on colorectal tumor cells

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

Monoclonal Antibodies for Analysis of the HLA System

1979 • 745 citations

Identification of human cancers deficient in antigen processing.

1993 • 625 citations

Natural history of HLA expression during tumour development

1993 • 448 citations

Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid.

1986 • 437 citations

Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.

1985 • 358 citations

Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas.

1994 • 333 citations

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.

1991 • 304 citations

Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines.

1983 • 257 citations

Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

1993 • 176 citations

Loss of HLA haplotype and B locus down-regulation in melanoma cell lines.

1994 • 163 citations

Distribution of HLA class 1 antigens in normal human tissue and in mammary cancer.

1981 • 153 citations

Diet and gastric cancer. A case‐control study in Belgium

1992 • 147 citations

Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors.

1994 • 143 citations

The HLA system: structure and function.

1987 • 131 citations

The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon.

1983 • 120 citations

Loss of HLA-A,B,C allele products and lymphocyte function-associated antigen 3 in colorectal neoplasia.

1989 • 119 citations

Tumor Escape from Immune Response by Variation in HLA Expression and Other Mechanisms

1993 • 107 citations

Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer.

1994 • 100 citations

Low‐resolution DNA typing for HLA‐B using sequence‐specific primers in allele‐ or group‐specific ARMS/PCR

1994 • 92 citations

Expression of major histocompatibility antigens and nature of inflammatory cellular infiltrate in ovarian neoplasms

1983 • 81 citations

Identification of tumour rejection antigens recognized by T lymphocytes.

1992 • 72 citations

Defining the common subtypes of HLA A9, A10, A28 and A19 by use of ARMS/PCR

1993 • 71 citations

Expression of HLA-A2 antigen in human melanoma cell lines and its role in T-cell recognition.

1991 • 63 citations

Loss of HLA class‐I alleles, heavy chains and β₂‐microglobulin in colorectal cancer

1992 • 61 citations

Studies on the mechanisms of invasion in cancer. I. Isolation and purification of a factor chemotactic for cancer cells

1970 • 51 citations

IMMUNOGENETIC FACTORS IN HPV‐ASSOCIATED CERVICAL CANCER: INFLUENCE ON DISEASE PROGRESSION

1996 • 50 citations

Frequency of abnormal expression of HLA-A,B,C and HLA-DR molecules, invariant chain, and LFA-3 (CD58) in colorectal carcinoma and its impact on tumor recurrence

1991 • 40 citations

Loss of Human Leukocyte Antigen Expression on Colorectal Tumor Cell Lines

1993 • 31 citations

A sensitive micro-immunoassay using β-galactosidase/ anti-β-galactosidase complexes

1987 • 29 citations

Molecular analysis of MHC-class-I alterations in human tumor cell lines

1991 • 25 citations

Variation in HLA Expression on Tumors: An Escape from Immune Response

1989 • 22 citations

Expression of MHC-class-I antigens in human carcinomas and sarcomas analyzed by isoelectric focusing

1991 • 20 citations