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Structure and chemistry of the copper chaperone proteins

Data up to Jan 2025

Published2000
Citations192
References50

Total Citations Per Year

Abstract

References (50)

Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

1999 • 1,573 citations

The Copper Chaperone for Superoxide Dismutase

1997 • 828 citations

Metal Ion Chaperone Function of the Soluble Cu(I) Receptor Atx1

1997 • 675 citations

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake

1994 • 659 citations

Characterization of , a Yeast Gene Involved in Copper Metabolism and Assembly of Cytochrome Oxidase

1996 • 483 citations

Copper—A “Modern” Bioelement

1996 • 471 citations

A Role for the Saccharomyces cerevisiae ATX1 Gene in Copper Trafficking and Iron Transport

1997 • 403 citations

Identification and Functional Expression of HAH1, a Novel Human Gene Involved in Copper Homeostasis

1997 • 372 citations

Wilson disease and Menkes disease: new handles on heavy-metal transport

1994 • 326 citations

NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein

2000 • 316 citations

Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis

1999 • 267 citations

The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity.

1995 • 265 citations

The Copper Chaperone CCS Directly Interacts with Copper/Zinc Superoxide Dismutase

1998 • 247 citations

Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

1998 • 238 citations

Purification, Characterization, and Localization of Yeast Cox17p, a Mitochondrial Copper Shuttle

1997 • 237 citations

Crystal structure of the Atx1 metallochaperone protein at 1.02 Å resolution

1999 • 226 citations

Identification of a Functional Homolog of the Yeast Copper Homeostasis Gene ATX1 from Arabidopsis1

1998 • 202 citations

Crystal structure of the copper chaperone for superoxide dismutase.

1999 • 194 citations

Structures of the Reduced and Mercury-Bound Forms of MerP, the Periplasmic Protein from the Bacterial Mercury Detoxification System,

1997 • 192 citations

Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly

1999 • 192 citations

Two trans-Acting Metalloregulatory Proteins Controlling Expression of the Copper-ATPases of Enterococcus hirae*

1995 • 190 citations

Multiple Protein Domains Contribute to the Action of the Copper Chaperone for Superoxide Dismutase

1999 • 186 citations

Suppressors of Superoxide Dismutase (SOD1) Deficiency in Saccharomyces cerevisiae

1998 • 183 citations

Characterization of the Interaction between the Wilson and Menkes Disease Proteins and the Cytoplasmic Copper Chaperone, HAH1p

1999 • 168 citations

The Enterococcus hirae copper chaperone CopZ delivers copper(I) to the CopY repressor

1999 • 167 citations

Structure-Function Analyses of the ATX1 Metallochaperone

1999 • 143 citations

NMR Structure and Metal Interactions of the CopZ Copper Chaperone

1999 • 125 citations

The Copper Chaperone CCS Is Abundant in Neurons and Astrocytes in Human and Rodent Brain

1999 • 123 citations

CopY Is a Copper-inducible Repressor of the Enterococcus hirae Copper ATPases

1997 • 111 citations

Characterization of the Copper Chaperone Cox17 of Saccharomyces cerevisiae

1998 • 104 citations

Familial amyotrophic lateral sclerosis

1997 • 96 citations

Crystal Structure of the Second Domain of the Human Copper Chaperone for Superoxide Dismutase,

2000 • 90 citations

Identification of Metal-Binding Residues in the Klebsiella aerogenes Urease Nickel Metallochaperone, UreE

1999 • 83 citations

A Gain of Superoxide Dismutase (SOD) Activity Obtained with CCS, the Copper Metallochaperone for SOD1

1999 • 78 citations

The Copper Transport Protein Atox1 Promotes Neuronal Survival

2000 • 78 citations

The genetic and molecular mechanisms of motor neuron disease

1998 • 74 citations

The Menkes Disease Protein Binds Copper via Novel 2-Coordinate Cu(I)−Cysteinates in the N-Terminal Domain

1998 • 59 citations

Expression of copper trafficking genes in the mouse brain

1998 • 58 citations

Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly

1999 • 48 citations

The Saccharomyces cerevisiae LYS7 gene is involved in oxidative stress protection

1998 • 42 citations

Incorporation of Molybdenum into the Iron-Molybdenum Cofactor of Nitrogenase

1999 • 33 citations

Roles of Copper Ligands in the Activation and Secretion ofStreptomyces Tyrosinase

1998 • 32 citations

Effects of Promoter Mutations on the in Vivo Regulation of the cop Operon of Enterococcus hirae by Copper(I) and Copper(II)

1999 • 29 citations

Expression profile of the copper homeostasis gene, rAtox1, in the rat brain

1999 • 27 citations

Familial amyotrophic lateral sclerosis

1997 • 23 citations

Helping copper find a home.

1999 • 22 citations

The Copper Chaperone Atox1 in Canine Copper Toxicosis in Bedlington Terriers

1999 • 20 citations

A model for the incorporation of metal from the copper chaperone CCS into Cu,Zn superoxide dismutase

1999 • 15 citations

Melatonin-induced changes in blood and pituitary luteinizing hormone and prolactin levels during the perinatal period in rat dams

1980 • 10 citations

Molecular Cloning of Rat ATX1 Homologue Protein

1999 • 9 citations

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