Activation of C1

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

The Proteolytic Activation Systems of Complement

1981 • 479 citations

Subunit composition and structure of subcomponent C1q of the first component of human complement

1976 • 326 citations

Proteins involved in the activation and control of the two pathways of human complement

1983 • 169 citations

A new role for C-1-inhibitor in homeostasis: control of activation of the first component of human complement.

1982 • 148 citations

Differential elution of Clq, Cl̄r and Cl̄s from human CT bound to immune aggregates. use in the rapid purification of Cl̄ sub-components

1979 • 141 citations

The structure and enzymic activities of the C1r and C1s subcomponents of C1, the first component of human serum complement

1977 • 129 citations

Measurement of the association constants of the complexes formed between intact C1q or pepsin-treated C1q stalks and the unactivated or activated C1r2C1s2 tetramers

1983 • 96 citations

Assembly of subcomponents C1r and C1s of first component of complement: electron microscopic and ultracentrifugal studies.

1980 • 66 citations

The Classical Complement Pathway: Mechanism of Activation of the First Component by Antigen-Antibody Complexes (Part 1 of 3)

1982 • 65 citations

Complete amino acid sequence of the catalytic chain of human complement subcomponent C.hivin.1r

1983 • 50 citations

Characterization of the C1q receptor on a human macrophage cell line, U937

1984 • 50 citations

The role of immune complexes in the activation of the first component of human complement.

1984 • 48 citations

Calcium binding properties of the C1 subcomponents C1q, C1r and C1s

1980 • 45 citations

The binding and activation of the C1r-C1s subunit of the first component of human complement

1982 • 41 citations

Size and shape of human CI‐inhibitor

1981 • 41 citations

Neutron scattering studies of subcomponent C1q of first component C1 of human complement and its association with subunit C1r2C1s2 within C1

1984 • 33 citations

The Classical Complement Pathway: Mechanism of Activation of the First Component by Antigen-Antibody Complexes

2015 • 30 citations

Dissociation of C1 and concentration dependence of its activation kinetics

1982 • 28 citations

The serine proteinase chain of human complement component C̅1s. Cyanogen bromide cleavage and N-terminal sequences of the fragments

1983 • 26 citations

Neutron scattering studies of the isolated C1r2C1s2 subunit of first component of human complement in solution.

1983 • 20 citations

Autoactivation of human complement subcomponent C1r involves structural changes reflected in modifications of intrinsic fluorescence, circular dichroism and reactivity with monoclonal antibodies

1983 • 15 citations

The Croonian Lecture, 1980 - The complex proteases of the complement system

1980 • 15 citations

Diamine-induced dissociation of the first component of human complement, C1

1984 • 14 citations