Hormone-refractory (D3) prostate cancer: Refining the concept

A Controlled Trial of Leuprolide with and without Flutamide in Prostatic Carcinoma

1989 • 1,494 citations

Stratification of patients with metastatic prostate cancer based on extent of disease on initial bone scan

1988 • 618 citations

The TNM classification of prostate cancer

1992 • 475 citations

Treatment of metastatic prostatic cancer with low-dose prednisone: evaluation of pain and quality of life as pragmatic indices of response.

1989 • 417 citations

Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer.

1993 • 417 citations

Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma.

1981 • 382 citations

Hormone therapy in prostatic cancer

1956 • 283 citations

Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer.

1992 • 237 citations

Neuroendocrine differentiation in human prostatic carcinoma

1992 • 236 citations

Nuclear androgen receptors in the epithelium and stroma of human benign prostatic hypertrophic glands

1983 • 188 citations

Prostate-specific antigen decline after casodex withdrawal: Evidence for an antiandrogen withdrawal syndrome

1994 • 174 citations

Use of palliative end points to evaluate the effects of mitoxantrone and low-dose prednisone in patients with hormonally resistant prostate cancer.

1994 • 169 citations

Response to Flutamide Withdrawal in Advanced Prostate Cancer in Progression Under Combination Therapy

1993 • 139 citations

Surprising Activity of Flutamide Withdrawal, When Combined With Aminoglutethimide, in Treatment of "Hormone-Refractory" Prostate Cancer

1994 • 137 citations

Suramin, an Active Drug for Prostate Cancer: Interim Observations in a Phase I Trial

1993 • 133 citations

Phase II evaluation of coumarin (1,2‐benzopyrone) in metastatic prostatic carcinoma

1992 • 92 citations

Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma

1984 • 86 citations

Orchiectomy versus goserelin and flutamide in the treatment of newly diagnosed metastatic prostate cancer. Analysis of the criteria of evaluation used in the european organization for research and treatment of cancer–-genitourinary group study 30853

1993 • 86 citations

Criteria for Evaluating Patient Responses to Treatment Modalities for Prostatic Cancer

1984 • 86 citations

Mechanism of the glucocorticoid regulation of growth of the androgen-sensitive prostate-derived R3327H-G8-A1 tumor cell line.

1985 • 77 citations

Benefits of Combination Therapy with Flutamide in Patients Relapsing after Castration

1988 • 72 citations

CORTICAL STEROIDS IN TREATMENT OF CANCER

1950 • 67 citations

Case Reports

1995 • 66 citations

Case Reports: Withdrawal Phenomenon With the Antiandrogen Casodex

1995 • 65 citations

Cortisone Treatment in Advanced Carcinoma of the Prostate

1954 • 62 citations

Clinical and Biochemical Effect of Aminoglutethimide in the Treatment of Advanced Prostatic Carcinoma

1983 • 59 citations

Androgen Suppression by Hydrocortisone without Aminoglutethimide in Orchiectomised Men with Prostatic Cancer

1987 • 58 citations

Suramin for prostatic cancer: A phase I/II study in advanced extensively pretreated disease

1990 • 57 citations

Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer

1984 • 44 citations

Treatment of advanced prostatic cancer, resistant to conventional therapy with aminoglutethimide

1985 • 42 citations

A phase II randomized trial of megestrol acetate or dexamethasone in the treatment of hormonally refractory advanced carcinoma of the prostate

1990 • 30 citations

Anti‐hormone Treatment for Prostate Cancer Relapsing after Treatment with Flutamide and Castration

1989 • 27 citations

A Study of Aminoglutethemide and Hydrocortisone in Patients with Advanced and Refractory Prostate Carcinoma

1989 • 18 citations

Evaluation of Aminoglutethimide in Stage D Prostate Cancer: An Assessment of Efficacy ani Toxicity in Patients With Tumors Refractory to Hormonal Therapy

1984 • 13 citations

Medical Adrenalectomy for Advanced Prostatic Cancer

1988 • 8 citations

Treatment of Stage D2 Prostatic Cancer Refractory to or Relapsed following Castration plus Oestrogens

1990 • 8 citations

[Immunotherapy with transfer factor in hormone-resistant metastasized carcinoma of the prostate].

1989 • 3 citations