Dendritic cells transfected with PD-L1 recombinant adenovirus induces T cell suppression and long-term acceptance of allograft transplantation

Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells

2002 • 917 citations

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

2009 • 547 citations

Dendritic cells in the thymus contribute to T-regulatory cell induction

2008 • 292 citations

Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells

2009 • 253 citations

Dendritic Cells Genetically Engineered to Express Fas Ligand Induce Donor-Specific Hyporesponsiveness and Prolong Allograft Survival

2000 • 237 citations

Programmed Death Ligand 1 Regulates a Critical Checkpoint for Autoimmune Myocarditis and Pneumonitis in MRL Mice

2008 • 177 citations

RETROVIRAL DELIVERY OF VIRAL INTERLEUKIN-10 INTO MYELOID DENDRITIC CELLS MARKEDLY INHIBITS THEIR ALLOSTIMULATORY ACTIVITY AND PROMOTES THE INDUCTION OF T-CELL HYPORESPONSIVENESS1,2

1998 • 163 citations

High PD-L1/CD86 Ratio on Plasmacytoid Dendritic Cells Correlates With Elevated T-Regulatory Cells in Liver Transplant Tolerance

2008 • 150 citations

Involvement of the Programmed Death-1/Programmed Death-1 Ligand Pathway in CD4+CD25+ Regulatory T-Cell Activity to Suppress Alloimmune Responses

2007 • 131 citations

Costimulation blockade in autoimmunity and transplantation

2008 • 110 citations

Functional Plasticity of Dendritic Cell Subsets as Mediated by CD40 Versus B7 Activation

2003 • 108 citations

Adenoviral delivery of CTLA4Ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients

1999 • 103 citations

Impact of Immunosuppressive Drugs on CD4+CD25+FOXP3+ Regulatory T Cells: Does In Vitro Evidence Translate to the Clinical Setting?

2008 • 102 citations

OX40 costimulation can abrogate Foxp3⁺ regulatory T cell‐mediated suppression of antitumor immunity

2009 • 74 citations

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

2008 • 64 citations

Recombinant vesicular stomatitis virus targeted to Her2/neu combined with anti-CTLA4 antibody eliminates implanted mammary tumors

2008 • 58 citations

CD80 (B7-1) and CD86 (B7-2) are Functionally Equivalent in the Initiation and Maintenance of CD4⁺T-Cell Proliferation after Activation with Suboptimal Doses of PHA

2002 • 52 citations

Dysregulated B7-1 and B7-2 Expression on Nonobese Diabetic Mouse B Cells Is Associated with Increased T Cell Costimulation and the Development of Insulitis

2005 • 46 citations

Role of regulatory dendritic cells in allergy and asthma

2005 • 42 citations

Suppression of Human T-Cell Activation and Expansion of Regulatory T Cells by Pig Cells Overexpressing PD-Ligands

2009 • 41 citations

2B4 (CD244) signaling via chimeric receptors costimulates tumor-antigen specific proliferation and in vitro expansion of human T cells

2009 • 39 citations

Alloreactive CD8 T Cell Tolerance Requires Recipient B Cells, Dendritic Cells, and MHC Class II

2008 • 30 citations

Rapid Deletional Peripheral CD8 T Cell Tolerance Induced by Allogeneic Bone Marrow: Role of Donor Class II MHC and B Cells

2008 • 29 citations

TLR-9 signaling and TCR stimulation co-regulate CD8+ T cell-associated PD-1 expression

2009 • 26 citations

CELLULAR IMMUNE RESPONSES OF HUMAN CADAVER DONOR BONE MARROW CELLS AND THEIR SUSCEPTIBILITY TO COMMONLY USED IMMUNOSUPPRESSIVE DRUGS IN TRANSPLANTATION1

1998 • 25 citations

CD8+ T-Cell Depletion and Rapamycin Synergize with Combined Coreceptor/Stimulation Blockade to Induce Robust Limb Allograft Tolerance in Mice

2008 • 22 citations

Impaired negative regulation of homeostatically proliferating T cells

2008 • 18 citations

Biomarkers of the immunomodulatory effect of immunosuppressive drugs in transplant recipients

2009 • 17 citations

CTLA4Ig and the therapeutic potential of T cell co-stimulation blockade.

2008 • 16 citations

Mechanisms of Survival Prolongation of Murine Cardiac Allografts Using the Treatment of CTLA4-Ig and MR1

2008 • 15 citations

IddLoci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice

2008 • 15 citations

Enhanced Levels of Costimulation Lead to Reduced Effector/Memory CD8+ T Cell Functionality

2007 • 9 citations

Tyrosine Phosphorylation of a Novel 100‐kDa Protein Coupled to CD28 in Resting Human T Cells Is Enhanced by a Signal through TCR/CD3 Complex

2003 • 4 citations

CD8 T cell of donor splenocyte mixed with bone marrow cells is more effective than CD4 T cell for induction of donor-specific tolerance in sublethally irradiated mice

2004 • 1 citations