Transgenic Models for the Study of Lung Antioxidant Defense: Enhanced Manganese-containing Superoxide Dismutase Activity Gives Partial Protection to B6C3 Hybrid Mice Exposed to Hyperoxia
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References (41)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Detection of specific sequences among DNA fragments separated by gel electrophoresis
1975 • 33,059 citations
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
1979 • 22,482 citations
Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.
1980 • 8,711 citations
Biology of disease: free radicals and tissue injury.
1982 • 3,078 citations
A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.
1987 • 767 citations
[41] Preparation and assay of superioxide dismutases
1978 • 694 citations
Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen.
1980 • 678 citations
Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase.
1984 • 478 citations
Superoxide dismutase and pulmonary oxygen toxicity
1974 • 462 citations
The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles
1992 • 448 citations
Poly(A) signals
1991 • 438 citations
Overproduction of human Cu/Zn-superoxide dismutase in transfected cells: extenuation of paraquat-mediated cytotoxicity and enhancement of lipid peroxidation.
1986 • 322 citations
Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury.
1992 • 321 citations
Oxygen toxicity: augmentation of antioxidant defense mechanisms in rat lung
1976 • 216 citations
Superoxide mediates the toxicity of paraquat for cultured mammalian cells.
1988 • 197 citations
Cardioprotection by Cu, Zn-superoxide dismutase is lost at high doses in the reoxygenated heart
1990 • 157 citations
Isolation and characterization of complementary DNAs encoding human manganese‐containing superoxide dismutase
1988 • 146 citations
Protection against pulmonary oxygen toxicity in rats by the intratracheal administration of liposome-encapsulated superoxide dismutase or catalase.
1985 • 143 citations
Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity.
1991 • 141 citations
The role of endotoxin in protection of adult rats from oxygen-induced lung toxicity.
1978 • 137 citations
Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice
1991 • 133 citations
The cardioprotective effect of Mn-superoxide dismutase is lost at high doses in the postischemic isolated rabbit heart
1990 • 132 citations
Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia.
1987 • 122 citations
Alteration of endogenous glutathione peroxidase, manganese superoxide dismutase, and glutathione transferase activity in cells transfected with a copper-zinc superoxide dismutase expression vector. Explanation for variations in paraquat resistance.
1990 • 112 citations
Modulation of oxidant lung injury by using liposome-entrapped superoxide dismutase and catalase.
1985 • 92 citations
Human Mn superoxide dismutase cDNA sequence
1987 • 91 citations
A genetic model for evaluation of susceptibility to ozone-induced inflammation
1990 • 90 citations
Tracheal insufflation of tumor necrosis factor protects rats against oxygen toxicity
1990 • 82 citations
Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia
1989 • 80 citations
Inter-strain variation in susceptibility to hyperoxic injury of murine airways
1993 • 71 citations
Tolerance and cross-tolerance using NO2 and O2. I. Toxicology and biochemistry
1978 • 64 citations
Immunocytochemical localization of the sites of superoxide dismutase induction by hyperoxia in rat lungs.
1995 • 61 citations
Molecular basis for tumor necrosis factor-induced increase in pulmonary superoxide dismutase activities
1990 • 58 citations
Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants
1988 • 57 citations
Lung manganese superoxide dismutase increases during cytokine-mediated protection against pulmonary oxygen toxicity in rats.
1994 • 53 citations
Development of O2 tolerance in rabbits with no increase in antioxidant enzymes
1989 • 47 citations
Immunolocalization of manganese superoxide dismutase in normal and transgenic mice expressing the human enzyme
1993 • 38 citations
Protection against oxygen toxicity by tracheal insufflation of endotoxin: role of Mn SOD and alveolar macrophages
1994 • 34 citations
The effect of bacterial endotoxin on synthesis of (Cu,Zn)superoxide dismutase in lungs of oxygen-exposed rats.
1982 • 33 citations
Early divergent lung antioxidant enzyme expression in response to lipopolysaccharide
1996 • 21 citations