Tumor necrosis factor production by Kupffer cells requires protein kinase C activation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

The Gut as a Portal of Entry for Bacteremia Role of Protein Malnutrition

1987 • 468 citations

1-(5-isoquinol inesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase c in rabbit platelets

1984 • 437 citations

The Family of Protein Kinase C for Signal Transduction

1989 • 383 citations

Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings

1989 • 365 citations

Tumor necrosis factor and the acute metabolic response to tissue injury in man.

1988 • 300 citations

The activation of protein kinase C by biologically active lipid moieties of lipopolysaccharide.

1984 • 180 citations

Interferon-gamma modulates protein kinase C activity in murine peritoneal macrophages.

1985 • 170 citations

Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages.

1987 • 150 citations

Isolated parenchymal, Kupffer and endothelial rat liver cells characterized by their lysosomal enzyme content

1980 • 139 citations

The Albert Lasker Medical Awards. The family of protein kinase C for signal transduction

1989 • 111 citations

LPS induces altered phosphate labeling of proteins in murine peritoneal macrophages.

1986 • 88 citations

Endotoxin-Cell-Membrane Interactions Leading to Transmembrane Signaling

1981 • 73 citations

Protein kinase C: a potential pathway of endothelial cell activation by endotoxin, tumor necrosis factor, and interleukin-1.

1989 • 61 citations

Endotoxin Modulation of Hepatocyte Secretory and Cellular Protein Synthesis Is Mediated by Kupffer Cells

1988 • 53 citations

Inhibitors of protein kinase C block activation of B lymphocytes by bacterial lipopolysaccharide

1987 • 27 citations