Impact of Progestins on Estrogen-Induced Neuroprotection: Synergy by Progesterone and 19-Norprogesterone and Antagonism by Medroxyprogesterone Acetate

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

1996 • 1,640 citations

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1987 • 1,280 citations

Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer Risk

2000 • 1,075 citations

Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells.

1996 • 964 citations

Cardiovascular Health and Disease in Women

1993 • 803 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

Estrogen Replacement Therapy in Older Women

1994 • 596 citations

The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons

1999 • 581 citations

Estrogen-Induced Activation of Mitogen-Activated Protein Kinase in Cerebral Cortical Explants: Convergence of Estrogen and Neurotrophin Signaling Pathways

1999 • 474 citations

Estrogen improves psychological function in asymptomatic postmenopausal women.

1991 • 404 citations

Estrogen protects primary cortical neurons from glutamate toxicity

1996 • 329 citations

Gender influences outcome of brain injury: progesterone plays a protective role

1993 • 320 citations

Postmenopausal Estrogen Replacement Therapy and the Risk of Alzheimer's Disease: A Population-based Case-Control Study

1994 • 300 citations

The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus

2000 • 274 citations

Estradiol upregulates Bcl-2 expression in adult brain neurons

1998 • 253 citations

The Protooncogene bcl‐2 Inhibits Apoptosis in PC12 Cells

1993 • 222 citations

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

1995 • 193 citations

Estrogen, Cognition, and a Woman’s Risk of Alzheimer’s Disease

1997 • 191 citations

Determinants of Compliance with Anticoagulation: A Case-Control Study

1997 • 189 citations

Modulation of Bcl-2 expression

1998 • 173 citations

Protein Kinase Cδ Mediates Neurogenic but Not Mitogenic Activation of Mitogen-Activated Protein Kinase in Neuronal Cells

1999 • 172 citations

Regulation of progesterone receptor gene expression and growth in the rat uterus: modulation of estrogen actions by progesterone and sex steroid hormone antagonists.

1993 • 167 citations

Long-Term Estrogen Replacement Therapy in Female Patients with Dementia of the Alzheimer Type: 7 Case Reports

1995 • 151 citations

Estrogen-regulated developmental neuronal apoptosis is determined by estrogen receptor subtype and the Fas/Fas ligand system

2000 • 145 citations

Postmenopausal Estrogen and Estrogen-Progestin Use and 2-Year Rate of Cognitive Change in a Cohort of Older Japanese American Women

2000 • 144 citations

The female sex hormone oestrogen as a neuroprotectant

1999 • 137 citations

Prevention of endometrial cancer with progestogens

1986 • 126 citations

Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus

2000 • 126 citations

The postmenopausal estrogen/progestin interventions study: primary outcomes in adherent women

1997 • 125 citations

Progesterone in Conjunction With Estradiol Has Neuroprotective Effects in an Animal Model of Neurodegeneration

1999 • 116 citations

BCL-2 blocks glutamate toxicity in neural cell lines

1993 • 99 citations

Progesterone inhibits the estrogen-induced expression of c-fos messenger ribonucleic acid in the uterus.

1992 • 98 citations

The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus

2000 • 92 citations

Estrogen action in the reproductive tract of rhesus monkeys during antiprogestin treatment.

1993 • 87 citations

Antagonism between estradiol and progestin on Bcl-2 expression in breast-cancer cells

1996 • 87 citations

Oestrogen replacement therapy and Alzheimer's disease.

1996 • 73 citations

Rapid effects of gonadal steroids upon hypothalamic neuronal membrane ultrastructure

1987 • 67 citations

The estrogen replacement therapy of the Women’s Health Initiative promotes the cellular mechanisms of memory and neuronal survival in neurons vulnerable to Alzheimer’s disease

2000 • 64 citations

Effect of hormone replacement therapy on lipoprotein(a) and lipid levels in postmenopausal women. Influence of various progestogens and duration of therapy.

1996 • 62 citations

17β-Estradiol Induction of Filopodial Growth in Cultured Hippocampal Neurons within Minutes of Exposure

1993 • 57 citations

Increased risk of familial late-onset Alzheimer's disease in women

1996 • 37 citations

A women's health issue: Alzheimer's disease and strategies for maintaining cognitive health.

1999 • 35 citations

Effect of hormone replacement therapy on lipoprotein(a) and lipid levels in postmenopausal women. Influence of various progestogens and duration of therapy

1996 • 31 citations

Progesterone inhibits the estrogen-induced expression of c-fos messenger ribonucleic acid in the uterus

1992 • 29 citations

94290406 Estrogen replacement therapy in older women: Comparisons between Alzheimer's disease cases and nondemented control subjects

1995 • 21 citations

Use of progestogens in postmenopausal women.

1989 • 13 citations

Antagonism between estradiol and progestin on Bcl‐2 expression in breast‐cancer cells

1996 • 7 citations

The estrogen replacement therapy of the Women's Health Initiative promotes the cellular mechanisms of memory and neuronal survival in neurons vulnerable to Alzheimer's disease

2000 • 5 citations