A dose-comparison trial of topiramate as monotherapy in recently diagnosed partial epilepsy

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1972 • 27,145 citations

Proposal for Revised Classification of Epilepsies and Epileptic Syndromes

1989 • 5,132 citations

Early Identification of Refractory Epilepsy

2000 • 4,772 citations

Regression Analysis of Multivariate Incomplete Failure Time Data by Modeling Marginal Distributions

1989 • 1,774 citations

Comparison of Carbamazepine, Phenobarbital, Phenytoin, and Primidone in Partial and Secondarily Generalized Tonic–Clonic Seizures

1985 • 1,149 citations

Placebo-Controlled Trials and Active-Control Trials in the Evaluation of New Treatments. Part 1: Ethical and Scientific Issues

2000 • 862 citations

A Comparison of Valproate with Carbamazepine for the Treatment of Complex Partial Seizures and Secondarily Generalized Tonic–Clonic Seizures in Adults

1992 • 685 citations

Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy

1995 • 627 citations

Evaluation of Sample Size and Power for Analyses of Survival with Allowance for Nonuniform Patient Entry, Losses to Follow-Up, Noncompliance, and Stratification

1986 • 380 citations

A double-blind, randomized trial of topiramate in Lennox–Gastaut syndrome

1999 • 374 citations

Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold

1997 • 359 citations

Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-, and 1,000-mg daily dosages

1996 • 343 citations

Placebo-Controlled Trials and Active-Control Trials in the Evaluation of New Treatments. Part 2: Practical Issues and Specific Cases

2000 • 336 citations

A randomized, placebo-controlled study of topiramate in primary generalized tonic-clonic seizures

1999 • 293 citations

Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, and 600-mg daily dosages

1996 • 284 citations

Double‐Blind, Placebo‐Controlled Trial of Topiramate as Add‐on Therapy in Patients with Refractory Partial Seizures

1996 • 245 citations

Lamotrigine Monotherapy in Newly Diagnosed Untreated Epilepsy: A Double‐Blind Comparison with Phenytoin

1999 • 242 citations

A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children

1999 • 237 citations

Double‐Blind, Placebo‐Controlled Trial of Topiramate (600 mg Daily) for the Treatment of Refractory Partial Epilepsy

1996 • 192 citations

Double-blind, placebo-controlled study of topiramate in patients with refractory partial epilepsy

1996 • 169 citations

Topiramate Monotherapy for Partial Onset Seizures

1997 • 159 citations

Topiramate blocks perinatal hypoxia‐induced seizures in rat pups

2001 • 138 citations

Clinical Trials of Investigational Antiepileptic Drugs: Monotherapy Designs

1991 • 61 citations