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2000 • 6,348 citations

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2001 • 4,673 citations

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

2004 • 4,044 citations

Toll-like receptors in the induction of the innate immune response

2000 • 3,052 citations

Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

2002 • 1,919 citations

Differential Alteration in Intestinal Epithelial Cell Expression of Toll-Like Receptor 3 (TLR3) and TLR4 in Inflammatory Bowel Disease

2000 • 1,246 citations

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2003 • 1,124 citations

Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis

2004 • 859 citations

Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors

2000 • 754 citations

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

1999 • 638 citations

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1997 • 623 citations

Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells

2000 • 604 citations

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2001 • 571 citations

Human Peripheral Blood Cells Differentially Recognize and Respond to Two Distinct CpG Motifs

2001 • 518 citations

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2004 • 499 citations

Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation

2002 • 481 citations

Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

2004 • 465 citations

Bacterial Lipopolysaccharide and IFN-γ Induce Toll-Like Receptor 2 and Toll-Like Receptor 4 Expression in Human Endothelial Cells: Role of NF-κB Activation

2001 • 445 citations

Human Intestinal Epithelial Cells Are Broadly Unresponsive to Toll-Like Receptor 2-Dependent Bacterial Ligands: Implications for Host-Microbial Interactions in the Gut

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TNF-α and IFN-γ regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells

2003 • 407 citations

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2000 • 377 citations

Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis

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TLR4 and MD-2 Expression Is Regulated by Immune-mediated Signals in Human Intestinal Epithelial Cells

2002 • 355 citations

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2001 • 252 citations

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2002 • 191 citations

RETRACTED: DNA-PKcs Is Required for Activation of Innate Immunity by Immunostimulatory DNA

2000 • 180 citations

Bacterial DNA evokes epithelial IL‐8 production by a MAPK‐dependent, NFκB‐independent pathway

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Absence of Toll-Like Receptor 4 Explains Endotoxin Hyporesponsiveness in Human Intestinal Epithelium

2001 • 152 citations

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CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice

2002 • 127 citations

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2001 • 115 citations

CpG Oligodeoxynucleotides Modulate the Osteoclastogenic Activity of Osteoblasts via Toll-like Receptor 9

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