False positive staining in the TUNEL assay to detect apoptosis in liver and intestine is caused by endogenous nucleases and inhibited by diethyl pyrocarbonate

Statistical methods

1967 • 19,533 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Shrinkage necrosis: A distinct mode of cellular death

1971 • 1,448 citations

Stereological Methods

1982 • 1,198 citations

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

1995 • 1,171 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Molecular regulation of apoptosis: Genetic controls on cell death

1993 • 923 citations

A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA.

1993 • 823 citations

Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat.

1984 • 669 citations

Sampling designs for stereology*

1981 • 334 citations

Apoptosis and hepatobiliary disease

1995 • 268 citations

Effects of formaldehyde fixation on protein secondary structure: a calorimetric and infrared spectroscopic investigation.

1991 • 239 citations

Cell death by apoptosis: Basic concepts and disease relevance for the gastroenterologist

1996 • 191 citations

The evolution of changes in quantitative liver function tests in a rat model of biliary cirrhosis: Correlation with morphometric measurement of hepatocyte mass

1987 • 146 citations

Apoptosis is induced by transforming growth factor-beta 1 within 5 hours in regressing liver without significant fragmentation of the DNA.

1993 • 142 citations

Apoptosis is induced by transforming growth factor-β1 within 5 hours in regressing liver without significant fragmentation of the DNA

1993 • 111 citations

Reversibility of secondary biliary fibrosis by biliodigestive anastomosis in the rat

1992 • 106 citations

Apoptosis: a general comment

1991 • 81 citations

Deletion of hyperplastic biliary epithelial cells by apoptosis following removal of the proliferative stimulus

1985 • 77 citations