Growth factor stimulation triggers apoptotic cell death in mature oligodendrocytes

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

Apoptotic cell death induced by c-myc is inhibited by bcl-2

1992 • 981 citations

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

1991 • 861 citations

FGF modulates the PDGF-driven pathway of oligodendrocyte development

1990 • 586 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

Identification of an adult-specific glial progenitor cell

1989 • 476 citations

SERIAL GADOLINIUM ENHANCED MAGNETIC RESONANCE IMAGING IN MULTIPLE SCLEROSIS

1988 • 397 citations

Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds

1988 • 382 citations

The brain fibroblast growth factor (FGF) is localized in neurons

1986 • 276 citations

Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle.

1992 • 245 citations

BLOOD-BRAIN BARRIER DAMAGE IN ACUTE MULTIPLE SCLEROSIS PLAQUES

1991 • 235 citations

Oligodendrocyte progenitors isolated directly from developing telencephalon at a specific phenotypic stage: myelinogenic potential in a defined environment

1989 • 225 citations

Localization of basic fibroblast growth factor and its mRNA after CNS injury

1991 • 208 citations

A Study of Apoptosis in Normal and Pathologic Nervous Tissue After In situ End-Labeling of DNA Strand Breaks

1994 • 205 citations

Endothelial cell gene expression in response to injury

1993 • 194 citations

Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons

1992 • 192 citations

Expression of immunologically relevant endothelial cell activation antigens on isolated central neurvous system microvessels from patients with multiple sclerosis

1994 • 170 citations

RETINAL VENOUS SHEATHING IN OPTIC NEURITIS

1987 • 163 citations

Cytotoxic effects of cell cycle phase specific agents: result of cell cycle perturbation.

1990 • 144 citations

Inflammatory vasculitis in multiple sclerosis

1985 • 137 citations

Radioautographic evidence for slow astrocyte turnover and modest oligodendrocyte production in the corpus callosum of adult mice infused with3H-thymidine

1988 • 133 citations

Evidence that axons are mitogenic for oligodendrocytes isolated from adult animals

1986 • 113 citations

In vitro analysis of the oligodendrocyte lineage in mice during demyelination and remyelination.

1990 • 111 citations

Trophic effects of basic fibroblast growth factor (bFGF) on differentiated oligodendroglia: A mechanism for regeneration of the oligodendroglial lineage

1993 • 104 citations

Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block.

1994 • 90 citations

Mitosis and apoptosis of microgliain vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier

1993 • 78 citations

Ultrastructural localization of fibroblast growth factor in neurons of rat brain

1987 • 77 citations

Multiple sclerosis

1980 • 55 citations

Correlation Between Fibroblast Growth Factor Expression and Cell Proliferation in Experimental Brain Infarct: Studied with Proliferating Cell Nuclear Antigen Immunohistochemistry

1994 • 52 citations

The differentiation of glial cell progenitor populations following transplantation into non-repairing central nervous system glial lesions in adult animals

1992 • 51 citations

Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration

1993 • 45 citations

Basic fibroblast growth factor improves recovery after chemically induced breakdown of myelin‐like membranes in pure oligodendrocyte cultures

1994 • 30 citations

PDGF increases the expression of fos and jun in newly formed oligodendrocytes that have become resistant to the mitogenic effect of PDGF

1992 • 28 citations

Mitotic potential of adult rat oligodendrocytes in culture

1992 • 28 citations

CNS growth factors.

1990 • 24 citations