Choline acetyltransferase activity and [ 3H]vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)

1964 • 1,213 citations

Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease.

1985 • 570 citations

Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain

1984 • 454 citations

Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in alzheimer's disease

1985 • 407 citations

Behavioural, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats

1987 • 352 citations

Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase

1983 • 332 citations

Transmitter deficits in Alzheimer's disease

1985 • 326 citations

DEMENTIA

1982 • 284 citations

Muscarinic binding and choline acetyltransferase activity in Parkinsonian subjects with reference to dementia

1982 • 261 citations

Extensive loss of choline acetyltransferase activity is not reflected by neuronal loss in the nucleus of meynert in Alzheimer's disease

1982 • 239 citations

Nucleus basalis neuronal loss, neuritic plaques and choline acetyltransferase activity in advanced Alzheimer's disease

1986 • 210 citations

Pharmacological characterization of the acetylcholine transport system in purified Torpedo electric organ synaptic vesicles.

1983 • 181 citations

Cholinergic‐dependent cognitive deficits in Parkinson's disease

1987 • 177 citations

A subcortico-cortical cholinergic system is affected in Parkinson's disease

1983 • 176 citations

Laminar distribution of neocortical senile plaques in senile dementia of the alzheimer type

1986 • 154 citations

Demonstration of a receptor in Torpedo synaptic vesicles for the acetylcholine storage blocker L-trans-2-(4-phenyl[3,4-3H]-piperidino) cyclohexanol.

1986 • 116 citations

Changes in high affinity choline uptake in rat cortex following lesions of the magnocellular forebrain nuclei

1982 • 96 citations

Quantitative assessment of the density of neurofibrillary tangles and senile plaques in senile dementia of the Alzheimer type. Comparison of immunocytochemistry with a specific antibody and Bodian's protargol method

1987 • 90 citations

Cortical atrophy in senile dementia of the Alzheimer type is mainly due to a decrease in cortical length

1985 • 88 citations

Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease

1988 • 88 citations

[³H]vesamicol binding in brain: Autoradiographic distribution, pharmacology, and effects of cholinergic lesions

1988 • 80 citations

The basal nucleus of Meynert in idiopathic Parkinson's disease

2009 • 73 citations

Choline acetyltransferase-like immunoreactivity in the hippocampal formation of control subjects and patients with Alzheimer's disease

1989 • 70 citations

Quantitative autoradiography of brain binding sites for the vesicular acetylcholine transport blocker 2-(4-phenylpiperidino)cyclohexanol (AH5183).

1987 • 65 citations

POST MORTEM STABILITY AND STORAGE IN THE COLD OF BRAIN ENZYMES

1979 • 63 citations

Increased fragility of erythrocytes from amyotrophic lateral sclerosis (ALS) patients provoked by mechanical stress

1984 • 48 citations

Acetylcholine Transport: Fundamental Properties and Effects of Pharmacologic Agentsa

1987 • 41 citations

[Dementia and Parkinson's disease: biochemical and anatomo-clinical correlation].

1985 • 39 citations

Analytical Subcellular Fractionation of Rat Cortex: Resolution of Serotonergic Nerve Endings and Receptors

1983 • 22 citations

FIBRE DISORGANIZATION IN THE NEOCORTEX OF PATIENTS WITH SENILE DEMENTIA OF THE ALZHEIMER TYPE

1989 • 22 citations