In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

1991 • 1,014 citations

Induction of Pemphigus in Neonatal Mice by Passive Transfer of IgG from Patients with the Disease

1982 • 667 citations

Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells

1992 • 280 citations

Mucosal and Mucocutaneous (Generalized) Pemphigus Vulgaris Show Distinct Autoantibody Profiles

1997 • 243 citations

Pemphigus and pemphigoid as paradigms of organ-specific, autoantibody-mediated diseases.

1989 • 196 citations

A Central Role for the Armadillo Protein Plakoglobin in the Autoimmune Disease Pemphigus Vulgaris

2001 • 193 citations

The Prevalence of Antibodies against Desmoglein 1 in Endemic Pemphigus Foliaceus in Brazil

2000 • 166 citations

Dominant Autoimmune Epitopes Recognized by Pemphigus Antibodies Map to the N-Terminal Adhesive Region of Desmogleins

2001 • 165 citations

Human autoantibodies against a desmosomal protein complex with a calcium-sensitive epitope are characteristic of pemphigus foliaceus patients.

1987 • 157 citations

The Anti-Desmoglein 1 Autoantibodies in Pemphigus Vulgaris Sera are Pathogenic

1999 • 131 citations

Pemphigoid and pemphigus antigens in cultured epidermal cells

1978 • 117 citations

Pemphigus vulgaris antigen, a desmoglein type of cadherin, is localized within keratinocyte desmosomes

1993 • 116 citations

Pemphigus IgG Activates and Translocates Protein Kinase C from the Cytosol to the Particulate/Cytoskeleton Fractions in Human Keratinocytes

1997 • 115 citations

Pemphigus IgG, but Not Bullous Pemphigoid IgG, Causes a Transient Increase in Intracellular Calcium and Inositol 1,4,5-Triphosphate in DJM-1 Cells, a Squamous Cell Carcinoma Line

1995 • 115 citations

Pharmacologic Evidence for Involvement of Phospholiphase C in Pemphigus IgG-Induced Inositol 1,4,5-Trisphosphate Generation, Intracellular Calcium Increase, and Plasminogen Activator Secretion in DJM-1 Cells, a Squamous Cell Carcinoma Line

1995 • 109 citations

Transmembrane Signaling for Adhesive Regulation of Desmosomes and Hemidesmosomes, and for Cell-Cell Detachment Induced by Pemphigus IgG in Cultured Keratinocytes: Involvement of Protein Kinase C

1999 • 109 citations

Pemphigus Vulgaris and Pemphigus Foliaceus Antibodies are Pathogenic in Plasminogen Activator Knockout Mice

1999 • 93 citations

Mechanisms of Acantholysis in Pemphigus Vulgaris: Role of IgG Valence

1997 • 73 citations

Demonstration of Pemphigus Antibodies on the Cell Surface of Murine Epidermal Cell Monolayers and their Internalization

1984 • 65 citations

Dexamethasone inhibits plasminogen activator activity in experimental pemphigus in vivo but does not block acantholysis.

1986 • 52 citations

Pemphigus IgG Induces Expression of Urokinase Plasminogen Activator Receptor on the Cell Surface of Cultured Keratinocytes

1997 • 49 citations

Phosphatidylcholine-specific phospholipase C, but not phospholipase D, is involved in pemphigus IgG-induced signal transduction

1999 • 49 citations

Mechanisms of Acantholysis in Pemphigus Foliaceus

1997 • 47 citations

Plasminogen activator system in pemphigus vulgaris

1996 • 34 citations

Involvement of Desmoplakin Phosphorylation in the Regulation of Desmosomes by Protein Kinase C, in HeLa Cells

1999 • 24 citations

Desmosomes are Regulated by Protein Kinase C in Primary Rat Epithelial Cells

1998 • 21 citations

Plasminogen activator system in pemphigus vulgaris

1996 • 3 citations

Deleted Work

1955 • 0 citations