The Two-dimensional polypeptide profile of terminally non-dividing human diploid cells*1

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

1970 • 1,002 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

Cellular senescence and DNA synthesis

1973 • 537 citations

Simple and rapid fluorimetric method for DNA microassay

1977 • 491 citations

T98G: An anchorage‐independent human tumor cell line that exhibits stationary phase G1 arrest in vitro

1979 • 304 citations

Intraclonal Variation in Proliferative Potential of Human Diploid Fibroblasts: Stochastic Mechanism for Cellular Aging

1980 • 290 citations

VARIATION IN THE LIFE-SPAN OF CLONES DERIVED FROM HUMAN DIPLOID CELL STRAINS

1974 • 272 citations

Identification of a nuclear and of a cytoplasmic polypeptide whose relative proportions are sensitive to changes in the rate of cell proliferation

1981 • 197 citations

Chapter 27 Two-Dimensional Polyacrylamide Gel Electrophoretic Fractionation

1977 • 149 citations

Proliferative capacity and DNA content of aging human diploid cells in culture: A cytophotometric and autoradiographic analysis

1974 • 141 citations

Comparative heterokaryon study of cellular senescence and the serum-deprived state

1980 • 92 citations

Entry into S phase is inhibited in two immortal cell lines fused to senescent human diploid cells

1979 • 91 citations

Senescence of cultured human fibroblasts: Mitotic versus metabolic time

1974 • 73 citations

Ongoing DNA synthesis continues in young human diploid cells (HDC) fused to senescent HDC, but entry into S phase is inhibited

1980 • 73 citations

Evidence for endogenous polypeptide-mediated inhibition of cell-cycle transit in human diploid cells.

1982 • 57 citations

Inhibition of DNA synthesis in proliferating human diploid fibroblasts by fusion with senescent cytoplasts*1

1983 • 49 citations

Variation, Senescence, and Neoplasia in Cultured Somatic Cells

1975 • 34 citations

Patterns of peptide synthesis in senescent and presenescent human fibroblasts

1979 • 27 citations

A long-lived human diploid fibroblast line for cellular aging studies: Applications in cell hybridization

1982 • 26 citations

Mechanisms of protein turnover in cultured fibroblasts

1980 • 24 citations

Skin fibroblast cultures derived from members of the Baltimore Longitudinal Study: a new resource for studies of cellular aging

1981 • 17 citations

Cumulative population doublings as the determinant of chick cell lifespan in vitro

1981 • 16 citations

Human diploid fibroblasts (HDF) can induce DNA synthesis in cycling HDF but not in quiescent HDF or senescent HDF*1

1983 • 6 citations