High performance liquid chromatography (HPLC) of arachidonic acid metabolites

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

1980 • 2,099 citations

The chemical structure of prostaglandin X (prostacyclin)

1976 • 729 citations

Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

1979 • 652 citations

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

1976 • 638 citations

The prostaglandins: a family of biologically active lipids.

1968 • 613 citations

Arachidonate lipoxygenase in blood platelets

1975 • 613 citations

Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

1979 • 556 citations

Biosynthesis of Prostaglandins

1991 • 503 citations

The enzymatic formation of prostaglandin E2 from arachidonic acid prostaglandins and related factors 32

1964 • 473 citations

Prostaglandins as Mediators of Hypercalcemia Associated with Certain Types of Cancer

1975 • 461 citations

Novel reagent for the fluorometric assay of primary amines

1972 • 461 citations

On the specific vaso‐dilating and plain muscle stimulating substances from accessory genital glands in man and certain animals (prostaglandin and vesiglandin)

1936 • 452 citations

Stereospecific total synthesis of a "slow reacting substance" of anaphylaxis, leukotriene C-1

1980 • 369 citations

Properties of human seminal plasma

1935 • 361 citations

Prostaglandins: Members of a New Hormonal System

1967 • 347 citations

The Isolation of Prostaglandin F from Sheep Prostate Glands.

1960 • 318 citations

Structure of leukotriene C identification of the amino acid part

1979 • 304 citations

Prostaglandins and Related Factors

1963 • 290 citations

The Structure of Prostaglandin E, F1 and F2.

1962 • 283 citations

Generation of unique mono-hydroxy-eicosatetraenoic acids from arachidonic acid by human neutrophils.

1979 • 258 citations

The Isolation of Prostaglandin E from Sheep Prostate Glands.

1960 • 246 citations

Preparation and assay of monohydroxy-eicosatetraenoic acids

1980 • 173 citations

Leukotriene a: Stereochemistry and enzymatic conversion to leukotriene B

1980 • 162 citations

Preparation and purification of arachidonic acid hydroperoxides of biological importance

1979 • 161 citations

The autoxidation of arachidonic acid: Formation of the proposed SRS-A intermediate

1979 • 140 citations

Biosynthesis of prostaglandin D2 1. Formation of prostaglandin D2 by human platelets

1977 • 140 citations

Stereochemistry of leukotriene C-1

1980 • 134 citations

Leukotriene A. Isolation from human polymorphonuclear leukocytes.

1980 • 133 citations

High performance liquid chromatography and UV detection for the separation and quantitation of prostaglandins

1981 • 117 citations

Determination of cyclooxygenase products and prostaglandin metabolites using high-pressure liquid chromatography and radioimmunoassay

1979 • 108 citations

Slow‐reacting substance of anaphylaxis Purification and characterisation

1978 • 107 citations

Biological/biomedical applications of liquid chromatography

1979 • 102 citations

Metabolism of prostaglandin D2 in the monkey.

1979 • 94 citations

Isomers of leukotriene B4 possess different biological potencies

1981 • 93 citations

Prostaglandins

1965 • 90 citations

The production and characterisation of products of the lipoxygenase enzyme system released by rat peritoneal macrophages

1980 • 87 citations

High performance liquid chromatographic determination of prostaglandins F2.alpha., E2, and D2 from in vitro enzyme incubations

1976 • 80 citations

Arachidonic acid metabolism by cells in culture: analyses of culture fluids for cyclooxygenase products by radioimmunoassay before and after separation by high pressure liquid chromatography

1979 • 77 citations

Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips.

1979 • 76 citations

Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite.

1977 • 75 citations

Oximes for high performance liquid and electron capture gas chromatography of prostaglandins and thromboxanes

1977 • 75 citations

Effects of phloretin and theophylline on 3-O-methylglucose transport by intestinal epithelial cells

1978 • 74 citations

Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography

1978 • 74 citations

Biological/biomedical applications of liquid chromatography

1980 • 73 citations

Transformation of arachidonic acid into monohydroxy‐eicosatetraenoic acids by mouse peritoneal macrophages

1981 • 71 citations

Complete separation by high performance liquid chromatography of metabolites of arachidonic acid from incubation with human and rabbit platelets

1980 • 69 citations

Reversed-phase high-performance liquid chromatography of prostaglandins — biological applications

1979 • 68 citations

Prostaglandin-mediated hypercalcemia in the VX2 carcinoma-bearing rabbit

1977 • 60 citations

High performance liquid chromatography of prostaglandins: Biological applications

1976 • 55 citations

Determination of 15-keto-13,14-dihydro-metabolites of PGE2 and PGF2α in plasma using high performance liquid chromatography and gas chromatography-mass spectrometry

1976 • 52 citations

Selective inhibitors of platelet lipoxygenase: 4,7,10,13-icosatetraynoic acid and 5,8,11,14-henicosatetraynoic acid

1981 • 48 citations

Ionic milieu and control of K permeability in the parotid gland

1978 • 48 citations

11- leukotriene C: A naturally occurring slow reacting substance

1980 • 44 citations

Identification of the major urinary metabolite of thromboxane B2 in the monkey

1977 • 44 citations

Metabolism of thromboxane B2 in the monkey

1978 • 44 citations

High-performance liquid chromatography of p-nitrophenacyl esters of selected prostaglandins on silver ion-loaded microparticulate cation-exchange resin

1977 • 37 citations

Separation of icosenoic acids, monohydroxyicosenoic acids, and prostaglandins by high-pressure liquid chromatography on a silver ion-loaded cation-exchange column

1981 • 35 citations

Identification and quantitative determination of prostaglandins by high pressure liquid chromatography

1974 • 33 citations

High-speed liquid chromatographic analysis of prostaglandins in rat kidney

1973 • 32 citations

Degradation Studies on Prostaglandins. Prostaglandins and Related Factors 10.

1963 • 29 citations

Separation of prostaglandins, thromboxane, hydroxy fatty acids and arachidonic acid by high pressure liquid chromatography

1980 • 29 citations

Application of high performance liquid chromatography and gas chromatography—Mass spectrometry to analysis of prostaglandin E1 in biological media

1979 • 26 citations

Determination of 5-trans-prostaglandin E2 in prostaglandin E2 via high performance liquid chromatography of their p-nitrophenacyl esters on a silver ion-loaded cation exchange resin

1976 • 23 citations

Separation of prostaglandins E1, E2, F1 and F2 by reversed-phase high-performance liquid chromatography

1979 • 22 citations

Simple and rapid separation of certain prostaglandins by reversed-phase high-performance liquid chromatography

1980 • 20 citations

The Prostaglandins

1967 • 16 citations

Quantitative determination of 15-epi-PGF2α in PGF2α

1972 • 15 citations

Purification and Some Physicochemical Properties of Slow‐Reacting Substance of Anaphylaxis (SRS‐A) from Sensitized Guinea Pig Lung

1979 • 14 citations

Redistribution of intrarenal blood flow following adh administration: Lack of inhibition by blockade of prostaglandin cyclooxygenase

1978 • 9 citations

The role of renal metabolism of PGE2 in determining its activity as a renal vasodilator in the dog

1979 • 9 citations

The partial purification of slow reacting substance of anaphylaxis from rat peritoneal anaphylactic fluid and its separation from an arachidonic acid releasing substance

1980 • 7 citations