Who's competent and when: regulation of natural genetic competence in bacteria

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES

1944 • 3,183 citations

Inactivation of Antibiotics and the Dissemination of Resistance Genes

1994 • 1,766 citations

Bacterial gene transfer by natural genetic transformation in the environment

1994 • 1,253 citations

Resistance to Antibiotics Mediated by Target Alterations

1994 • 671 citations

A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export

1995 • 589 citations

Biochemical and genetic characterization of a competence pheromone from B. subtilis

1994 • 457 citations

GENETIC NETWORKS CONTROLLING THE INITIATION OF SPORULATION AND THE DEVELOPMENT OF GENETIC COMPETENCE IN BACILLUS SUBTILIS

1995 • 406 citations

Common components in the assembly of type 4 fimbriae, DNA transfer systems, filamentous phage and protein‐secretion apparatus: a general system for the formation of surface‐associated protein complexes

1993 • 370 citations

Genetic competence in Bacillus subtilis

1991 • 367 citations

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis

1993 • 296 citations

Hybrid penicillin-binding proteins in penicillin-resistant strains of Neisseria gonorrhoeae

1988 • 248 citations

comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis

1995 • 229 citations

srfA is an operon required for surfactin production, competence development, and efficient sporulation in Bacillus subtilis

1991 • 227 citations

The Biology of Natural Transformation

1986 • 226 citations

Gene transfer in the environment

1990 • 218 citations

Frequency and Distribution of DNA Uptake Signal Sequences in the Haemophilus influenzae Rd Genome

1995 • 217 citations

The Clp proteins: proteolysis regulators or molecular chaperones?

1992 • 216 citations

Species-specific uptake of DNA by gonococci is mediated by a 10-base-pair sequence

1991 • 202 citations

Genetic Transformation

1981 • 200 citations

Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis.

1995 • 196 citations

A Bacillus subtilis regulatory gene product for genetic competence and sporulation resembles sensor protein members of the bacterial two-component signal-transduction systems.

1990 • 192 citations

DNA transformation leads to pilin antigenic variation in Neisseria gonorrhoeae

1988 • 188 citations

A gene required for nutritional repression of the Bacillus subtilis dipeptide permease operon

1995 • 178 citations

Genes for Breakfast: The Have-Your-Cake and-Eat-lt-Too of Bacterial Transformation

1993 • 176 citations

ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA

1993 • 174 citations

A small gene, designated comS, located within the coding region of the fourth amino acid‐activation domain of srfA, is required for competence development in Bacillus subtilis

1995 • 172 citations

Reassortment of pilin genes in Neisseria gonorrhoeae occurs by two distinct mechanisms

1989 • 167 citations

Gene transfer in the environment

1989 • 161 citations

Genetic transformation in Streptococcus pneumoniae: nucleotide sequence analysis shows comA, a gene required for competence induction, to be a member of the bacterial ATP-dependent transport protein family

1991 • 158 citations

Factors affecting genetic transformation of Neisseria gonorrhoeae

1977 • 152 citations

ComEA, a Bacillus subtilis integral membrane protein required for genetic transformation, is needed for both DNA binding and transport

1995 • 148 citations

comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis

1994 • 148 citations

Translocation of DNA across bacterial membranes

1994 • 140 citations

Shuttle mutagenesis of Neisseria gonorrhoeae: pilin null mutations lower DNA transformation competence

1990 • 125 citations

The regulation of competence transcription factor synthesis constitutes a critical control point in the regulation of competence in Bacillus subtilis

1994 • 99 citations

Growth stage signal transduction and the requirements for srfA induction in development of competence

1991 • 90 citations

Transposon mutagenesis, characterization, and cloning of transformation genes of Haemophilus influenzae Rd

1989 • 84 citations

The primary role of comA in establishment of the competent state in Bacillus subtilis is to activate expression of srfA

1991 • 83 citations

Novel determinant (comA) essential for natural transformation competence in Neisseria gonorrhoeae and the effect of a comA defect on pilin variation

1993 • 83 citations

DNA UPTAKE IN HAEMOPHILUS TRANSFORMATION

1982 • 82 citations

Growth medium-independent genetic competence mutants of Bacillus subtilis

1990 • 73 citations

ComC is required for the processing and translocation of ComGC, a pilin‐like competence protein of Bacillus subtilis

1995 • 69 citations

Transformation inHaemophilus: A problem in membrane biology

1984 • 65 citations

DNA repair and the evolution of transformation in Haemophilus influenzae.

1992 • 61 citations

The Haemophilus influenzae adenylate cyclase gene: cloning, sequence, and essential role in competence

1993 • 61 citations

Mutation of the putative nucleotide binding site of the Bacillus subtilis membrane protein ComFA abolishes the uptake of DNA during transformation

1994 • 56 citations

DNA repair and the evolution of transformation in Bacillus subtilis. III. Sex with damaged DNA.

1991 • 52 citations

The Haemophilus influenzae sxy-1 mutation is in a newly identified gene essential for competence

1994 • 39 citations

Sequence of the rec-2 locus of Haemophilus influenzae: homologies to comE-ORF3 of Bacillus subtilis and msbA of Escherichia coli

1994 • 34 citations

Bacterial Transformation

1979 • 33 citations