CD4⁺ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor‐associated determinants on effector cells by interleukin‐4 secretion

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

"Panning" for lymphocytes: a method for cell selection.

1978 • 1,319 citations

Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones

1991 • 1,027 citations

Two types of mouse helper T-cell clone

1987 • 813 citations

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

1989 • 588 citations

Functional diversity of T lymphocytes due to secretion of different cytokine patterns

1991 • 530 citations

A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.

1989 • 455 citations

Vaccination Against Experimental Allergic Encephalomyelitis with T Cell Receptor Peptides

1989 • 416 citations

IL-10, a novel growth cofactor for mature and immature T cells.

1990 • 371 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T–T cell interactions

1988 • 324 citations

Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

1989 • 289 citations

Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. II. Suppression of disease and in vitro immune responses is mediated by antigen-specific CD8+ T lymphocytes.

1989 • 284 citations

MRC OX-22, a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen.

1983 • 243 citations

Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4⁺ T cells

1991 • 218 citations

T Cell Receptor Peptide Therapy Triggers Autoregulation of Experimental Encephalomyelitis

1991 • 202 citations

Control of Experimental Autoimmune Encephalomyelitis by T Cells Responding to Activated T Cells

1989 • 197 citations

CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encephalomyelitis through a mechanism involving transforming growth factor-beta.

1991 • 175 citations

Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4).

1987 • 161 citations

A suppressor T-lymphocyte cell line for autoimmune encephalomyelitis

1988 • 138 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype.

1989 • 125 citations

Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells.

1990 • 117 citations

Vaccination against autoimmune encephalomyelitis (EAE): Attenuated autoimmune T lymphocytes confer resistance to induction of active EAE but not to EAE mediated by the intact T lymphocyte line

1981 • 108 citations

Regulation of experimental allergic encephalomyelitis. II. Appearance of suppressor cells during the remission phase of the disease.

1980 • 101 citations

Immunological Diseases

1989 • 91 citations

Transforming growth factors β1 and β2: cytokines with identical immunosuppressive effects and a potential role in the regulation of autoimmune T cell function

1989 • 84 citations

Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis.

1988 • 83 citations

Antibodies specific for VB8 receptor peptide suppress experimental autoimmune encephalomyelitis.

1990 • 82 citations

Evidence for suppressor cells in Lewis rats' experimental allergic encephalomyelitis

1977 • 80 citations

Autoimmune effector cells. II. Transfer of experimental allergic encephalomyelitis with a subset of T lymphocytes

1982 • 77 citations

CD4+ suppressor cells differentially affect the production of IFN-gamma by effector cells of experimental autoimmune encephalomyelitis.

1989 • 71 citations

[37] Experimental allergic encephalomyelitis

1988 • 52 citations

Experimental Allergic Encephalomyelitis in Lewis Rats: Chemical Synthesis of Disease-Inducing Determinant

1977 • 39 citations

Studies of Vβ8 T cell receptor peptide treatment in experimental autoimmune encephalomyelitis

1992 • 33 citations

Regulation of self tolerance in experimental allergic encephalomyelitis. I. Differences between lymph node and spleen suppressor cells.

1978 • 30 citations

Protection against experimental autoimmune encephalomyelitis requires both CD4+ T suppressor cells and myelin basic protein-primed B cells

1991 • 30 citations

Regulation of Self Tolerance in Experimental Allergic Encephalomyelitis

1978 • 26 citations

Lymphokine regulation of surface Ia expression on rat B cells

1988 • 12 citations

Effector cells of autoimmune encephalomyelitis in the rat belong to the CD4-positive, OX22-adherent T cell subset

1989 • 9 citations

Immune response to Schistosoma mansoni infections in inbred rats. VII. Resistance is contingent on OX-8(+)-regulated high affinity IL-2 receptor-bearing W3/25+ lymphocytes but not on IL-4-dependent cells.

1991 • 4 citations