New approaches to developing antimicrobials for resistant bacteria

Morpholino Antisense Oligomers: Design, Preparation, and Properties

1997 • 1,052 citations

Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa : Novel Agents for Combination Therapy

2001 • 844 citations

In Vitro and In Vivo Antibacterial Activities of a Novel Glycylcycline, the 9- t -Butylglycylamido Derivative of Minocycline (GAR-936)

1999 • 414 citations

Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial

2000 • 405 citations

Accessory Gene Regulator ( agr ) Locus in Geographically Diverse Staphylococcus aureus Isolates with Reduced Susceptibility to Vancomycin

2002 • 360 citations

Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents

2000 • 183 citations

Quorum sensing: a novel target for anti-infective therapy

1998 • 175 citations

Peptide Deformylase as an Antibacterial Drug Target: Target Validation and Resistance Development

2001 • 124 citations

Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site

2001 • 113 citations

The new antibiotics

1999 • 110 citations

N-Alkyl Urea Hydroxamic Acids as a New Class of Peptide Deformylase Inhibitors with Antibacterial Activity

2002 • 109 citations

Genomics and Antimicrobial Drug Discovery

1999 • 107 citations

Screening of natural products for antimicrobial agents

1990 • 102 citations

In Vitro Activities of Sitafloxacin (DU-6859a) and Six Other Fluoroquinolones against 8,796 Clinical Bacterial Isolates

2000 • 91 citations

Mn(III) Pyrophosphate as an Efficient Tool for Studying the Mode of Action of Isoniazid on the InhA Protein of Mycobacterium tuberculosis

2002 • 80 citations

In vitro antibacterial activity of LY333328, a new semisynthetic glycopeptide

1997 • 74 citations

Past, present, and future of antimicrobial agents

1995 • 62 citations

The history of antibiotics: The Japanese story

2002 • 50 citations

Restoration of Vancomycin Susceptibility in Enterococcus faecalis by Antiresistance Determinant Gene Transfer

2001 • 27 citations

In Vitro Activities of Novel Nonfluorinated Quinolones PGE 9262932 and PGE 9509924 against Clinical Isolates of Staphylococcus aureus and Streptococcus pneumoniae with Defined Mutations in DNA Gyrase and Topoisomerase IV

2002 • 24 citations