The gap junction: a channel for multiple functions?

Junctional intercellular communication: the cell-to-cell membrane channel.

1981 • 1,268 citations

Connexin43: a protein from rat heart homologous to a gap junction protein from liver.

1987 • 1,111 citations

Junctional intercellular communication and the control of growth

1979 • 965 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes

1986 • 790 citations

Molecular cloning of cDNA for rat liver gap junction protein.

1986 • 715 citations

Structure of the junction between communicating cells

1980 • 697 citations

MOLECULAR PROPERTIES OF VOLTAGE-SENSITIVE SODIUM CHANNELS

1986 • 577 citations

Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue

1977 • 571 citations

The major intrinsic protein (MIP) of the bovine lens fiber membrane: Characterization and structure based on cDNA cloning

1984 • 525 citations

Gap junction structures: Analysis of the x-ray diffraction data

1977 • 501 citations

Transmission of hormonal stimulation by cell-to-cell communication

1978 • 490 citations

Physiology and Pharmacology of Gap Junctions

1985 • 452 citations

Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein.

1986 • 443 citations

Antibodies to gap-junctional protein selectively disrupt junctional communication in the early amphibian embryo

1984 • 434 citations

Growth inhibition of transformed cells correlates with their junctional communication with normal cells

1986 • 416 citations

Two configurations of a channel-forming membrane protein

1984 • 368 citations

Gap junction structures. I. Correlated electron microscopy and x-ray diffraction.

1977 • 341 citations

Oscillations of cytosolic Ca2+ in pituitary cells due to action potentials

1987 • 331 citations

Two homologous protein components of hepatic gap junctions

1987 • 284 citations

Heterogeneity and contact-dependent regulation of hormone secretion by individual B cells

1986 • 256 citations

Interaction of anaesthetics with electrical synapses

1980 • 245 citations

STEREOLOGICAL ANALYSIS OF THE GUINEA PIG PANCREAS

1974 • 239 citations

Glucose-induced insulin release depends on functional cooperation between islet cells.

1982 • 231 citations

The cell-to-cell channel of gap junctions

1987 • 206 citations

Topological analysis of the major protein in isolated intact rat liver gap junctions and gap junction-derived single membrane structures.

1987 • 205 citations

Insulin, Glucagon, and Somatostatin Secretion in the Regulation of Metabolism

1978 • 205 citations

The Possible Importance of Contact between Pancreatic Islet Cells for the Control of Insulin Release*

1982 • 184 citations

Gap junctional communication and compaction during preimplantation stages of mouse development

1987 • 181 citations

The insulin factory: a tour of the plant surroundings and a visit to the assembly line

1985 • 172 citations

Expression of Functional Cell-Cell Channels from Cloned Rat Liver Gap Junction Complementary DNA

1987 • 166 citations

Acetylcholine Receptor Structure, Function, and Evolution

1985 • 165 citations

The Gap Junction

1986 • 164 citations

Homologies between gap junction proteins in lens, heart and liver

1988 • 160 citations

Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion.

1979 • 152 citations

Gap Junctional Communication

1981 • 152 citations

A protein homologous to the 27,000 dalton liver gap junction protein is present in a wide variety of species and tissues

1984 • 150 citations

Structural coupling between pancreatic islet cells

1973 • 145 citations

Temperature and energy dependence of secretory protein transport in the exocrine pancreas.

1986 • 140 citations

A morphological basis for intercellular communication between alpha- and beta-cells in the endocrine pancreas.

1975 • 138 citations

Electrical coupling between cells in islets of langerhans from mouse

1984 • 138 citations

Functional assembly of gap junction conductance in lipid bilayers: Demonstration that the major 27 kd protein forms the junctional channel

1987 • 131 citations

The Exocrine Pancreas: Biology, Pathobiology, and Diseases

1986 • 128 citations

Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells.

1988 • 128 citations

Immunolocalization of MP70 in lens fiber 16-17-nm intercellular junctions.

1987 • 124 citations

Gap junctions in several tissues share antigenic determinants with liver gap junctions.

1984 • 121 citations

Electrical coupling and uncoupling of exocrine acinar cells.

1978 • 112 citations

Islets of Langerhans: Dye Coupling Among Immunocytochemically Distinct Cell Types

1981 • 110 citations

Regulation of gap junctional conductance

1985 • 108 citations

Exocrine Pancreas: Evidence for Topographic Partition of Secretory Function

1975 • 99 citations

Activation of a calcium-dependent photoprotein by chemical signalling through gap junctions

1987 • 96 citations

Intercellular Communication in Pancreatic Islet Monolayer Cultures: A Microfluorometric Study

1979 • 95 citations

Hormone-induced intercellular signal transfer dissociates cyclic AMP-dependent protein kinase.

1984 • 95 citations

Physiological Roles of Permeable Junctions: Some Possibilities

1985 • 91 citations

Reduction of gap junctional conductance by microinjection of antibodies against the 27-kDa liver gap junction polypeptide.

1985 • 90 citations

Blockage of cell-to-cell communication within pancreatic acini is associated with increased basal release of amylase.

1986 • 83 citations

Isolated liver gap junctions: gating of transjunctional currents is similar to that in intact pairs of rat hepatocytes.

1986 • 81 citations

In Vivo Modulation of Gap Junctions and Dye Coupling Between B-Cells of the Intact Pancreatic Islet

1983 • 80 citations

Phorbol ester-mediated inhibition of intercellular communication in BALB/c 3T3 cells: relationship to enhancement of cell transformation.

1985 • 79 citations

Prolactin (in Vitro) Decreases the Glucose Stimulation Threshold, Enhances Insulin Secretion, and Increases Dye Coupling among Islet B Cells*

1987 • 79 citations

The functional integration of cells in animal tissues

1982 • 78 citations

Permeable Junctions Between Cardiac Cells

1981 • 75 citations

Cell Contacts in Human Islets of Langerhans

1975 • 73 citations

Pancreatic acinar cells: acetylcholine‐evoked electrical uncoupling and its ionic dependency

1978 • 72 citations

The gap junction.

1988 • 70 citations

Chemistry of Gap Junctions

1985 • 68 citations

Gap junctional coupling modulates secretion of exocrine pancreas.

1987 • 68 citations

Direct communication of homologous and heterologous endocrine islet cells in culture.

1982 • 67 citations

Gap Junction Development Is Correlated with Insulin Content in the Pancreatic B Cell

1980 • 67 citations

Evidence that Stimulation of Growth Hormone Release by Epinephrine and Vasoactive Intestinal Peptide Is Based on Cell-to-Cell Communication in the Pituitary*

1987 • 62 citations

Electron microscopic observations of reconstituted proteoliposomes with the purified major intrinsic membrane protein of eye lens fibers.

1987 • 62 citations

Caerulein and carbamoylcholine stimulate pancreatic amylase release at resting cytosolic free Ca2+

1986 • 62 citations

Nonrandom distribution of gap junctions between pancreatic beta-cells

1980 • 62 citations

Cell biology: Is there a common design for cell membrane channels?

1986 • 60 citations

Physiological Modulation of Gap Junction Permeability

1986 • 60 citations

Effects of n‐alcohols on junctional coupling and amylase secretion of pancreatic acinar cells

1989 • 59 citations

Metabolic coupling between cultured pancreatic B-cells

1981 • 52 citations

A dual population of islets of Langerhans in bovine pancreas

1980 • 51 citations

Gap junction structure and cell-to-cell coupling regulation: is there a calmodulin involvement?

1984 • 49 citations

Secretin induces rapid increases in inositol trisphosphate, cytosolic Ca2+ and diacylglycerol as well as cyclic AMP in rat pancreatic acini

1986 • 48 citations

Reversible effects of heptanol on gap junction structure and cell-to-cell electrical coupling.

1984 • 44 citations

Tissue and species conservation of the vertebrate and arthropod forms of the low molecular weight (16?18000) proteins of gap junctions

1988 • 43 citations

Decreased Glucose Stimulation Threshold, Enhanced Insulin Secretion, and Increased Beta Cell Coupling in Islets of Prolactin-Treated Rats

1987 • 43 citations

Analysis of the rat liver gap junction protein : clarification of anomalies in its molecular size

1988 • 40 citations

Antibody Probes in the Study of Gap Junctional Communication

1985 • 40 citations

Identification of a rat liver cDNA and mRNA coding for the 28 kDa gap junction protein

1986 • 39 citations

Cell-to-cell Communication in Rat Pancreatic Islet Monolayer Cultures is Modulated by Agents Affecting Islet-Cell Secretory Activity

1983 • 38 citations

The insulin cell: Its cellular environment and how it processes (Pro)insulin

1986 • 36 citations

Short and reversible uncoupling evokes little change in the gap junctions of pancreatic acinar cells

1983 • 35 citations

The gap junction proteins

1986 • 35 citations

In vivo modulation of gap junctions and dye coupling between B-cells of the intact pancreatic islet

1983 • 31 citations

Direct visualization of cell to cell coupling: transfer of fluorescent probes in living mammalian pancreatic acini

1979 • 29 citations

Gap junctions between pancreatic B-cells are modulated by cyclic AMP.

1985 • 29 citations

Morphometrical and immunocytochemical characterization of peri-insular and tele-insular acinar cells in the rat pancreas.

1985 • 28 citations

Glucose alters configuration of gap junctions between pancreatic islet cells

1986 • 24 citations

Amino acid transport in the rat exocrine pancreas

1978 • 23 citations

Regulation of Pancreatic Exocrine Function

1987 • 23 citations

The extent of dye-coupling between exocrine acinar cells of the mouse pancreas

1983 • 21 citations

Acetylcholine-evoked uncoupling restricts the passage of Lucifer Yellow between pancreatic acinar cells

1982 • 18 citations

Visualization of amylase secretion from individual pancreatic acini

1988 • 16 citations

Direct stimulation of enzyme secretion from rat exocrine pancreas by neurotensin and its naturally occurring fragments

1987 • 13 citations

Intercellular communication and cancer chemotherapy

1985 • 10 citations

Ciba Foundation Symposium 125 ‐ Junctional Complexes of Epithelial Cells

2007 • 8 citations

Differences in pancreatic enzyme release from ventral and dorsal areas of the rat pancreas

1986 • 4 citations

Diabetes Mellitus Type II

2006 • 2 citations