Flurbiprofen, a non-steroid anti-inflammatory agent, protects cells against hypoxic cell radiosensitizers in vitro

Clinical testing of the radiosensitizer Ro 07-0582: Experience with multiple doses

1977 • 264 citations

Hypoxic Sensitizers: Radiobiological Studies at the Cellular Level

1975 • 205 citations

Mechanism of microsomal and mitochondrial nitroreductase. Electron spin resonance evidence for nitroaromatic free radical intermediates

1975 • 195 citations

Binding to cellular macromolecules as a possible mechanism for the cytotoxicity of misonidazole.

1980 • 161 citations

Clinical Phase I Study of the Hypoxic Cell Radiosensitizer RO-07-0582, A 2-Nitroimidazole Derivative

1977 • 116 citations

Tests of Two Electron-Affinic Radiosensitizers in Vivo Using Regrowth of an Experimental Carcinoma

1975 • 115 citations

Genetics of Nitrofurazone Resistance in Escherichia coli

1978 • 112 citations

Breakage of bacterial DNA by nitrofuran derivatives.

1971 • 74 citations

Polyfunctional Radiosensitizers: I. Effects of a Nitroxyl Biradical on the Survival of Mammalian Cells in Vitro

1976 • 68 citations

Effect of nitrobenzene derivatives on electron transfer in cellular and chemical models.

1977 • 60 citations

Sulphydryls, ascorbate and oxygen as modifiers of the toxicity and metabolism of misonidazole in vitro

1980 • 49 citations

Damage to mammalian cell DNA by nitrofurans.

1975 • 48 citations

The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies.

1980 • 41 citations

The effect of dexamethasone on the radiation survival response and misonidazole-induced hypoxic-cell cytotoxicity in Chinese hamster cells V-79–753Bin vitro

1981 • 27 citations

Cytotoxic properties of a 4-nitroimidazole (NSC 38087): A radiosensitizer of hypoxic cells in vitro

1981 • 20 citations

Elevation of prostaglandin and cyclic AMP levels by arachidonic acid in primary epithelial cell cultures of C3H mouse mammary tumors

1977 • 18 citations

Variation in Cyclic Nucleotide Levels and Lysosomal Enzyme Activities in the Irradiated Rat

1980 • 15 citations

Initial clinical experience with the radiosensitizing nitroimidazole Ro 07-0582.

1977 • 14 citations

Serum concentrations of flurbiprofen in rheumatoid patients receiving large doses of flurbiprofen for long periods

1975 • 13 citations

Structure-function dependence and allopurinol inhibition of radiosensitizer/nitroreductase interaction: approaches to improving therapeutic ratios.

1980 • 9 citations