Purification and characterization of (Na+, K+)-ATPase. V. Conformational changes in the enzyme. Transitions between the Na-form and the K-form studied with tryptic digestion as a tool

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

CRYSTALLINE SOYBEAN TRYPSIN INHIBITOR

1947 • 2,416 citations

[1] Measurement of molecular weights by electrophoresis on SDS-acrylamide gel

1972 • 1,733 citations

Purification and characterization of (Na+ + K+)-ATPase III. Purification from the outer medulla of mammalian kidney after selective removal of membrane components by sodium dodecylsulphate

1974 • 936 citations

Activation by Adenosine Triphosphate in the Phosphorylation Kinetics of Sodium and Potassium Ion Transport Adenosine Triphosphatase

1972 • 826 citations

[4] Trypsinogens and trypsins of various species

1970 • 456 citations

Reversible Denaturation of Enzymes by Sodium Dodecyl Sulfate

1971 • 438 citations

Mechanisms in Bioenergetics

1965 • 422 citations

Disposition of the major proteins in the isolated erythrocyte membrane. Proteolytic dissection

1971 • 321 citations

[26] Isolation of (Na+ + K+)-ATPase

1974 • 279 citations

Properties of the Two Polypeptides of Sodium- and Potassium-dependent Adenosine Triphosphatase

1972 • 267 citations

Binding of ATP to brain microsomal ATPase Determination of the ATP-binding capacity and the dissociation constant of the enzyme-ATP complex as a function of K+ concentration

1971 • 263 citations

The (Na⁺+K⁺) activated enzyme system and its relationship to transport of sodium and potassium

1974 • 259 citations

A Method for Characterizing the Type and Numbers of Groups Involved in Enzyme Action

1961 • 236 citations

Purification and characterization of (Na+ + K+)-ATPase IV. Estimation of the purity and of the molecular weight and polypeptide content per enzyme unit in preparations from the outer medulla of rabbit kidney

1974 • 211 citations

Isolation and characterization of the components of the sodium pump

1974 • 205 citations

Enzymatic aspects of active linked transport of Na+ and K+ through the cell membrane

1964 • 204 citations

Surface Particles of Sarcoplasmic Reticulum Membranes

1974 • 193 citations

Mechanisms in Bioenergetics

1973 • 173 citations

The dispositions of proteins in the plasma membranes of animal cells: Analytical approaches using controlled peptidolysis and protein labels

1972 • 144 citations

Tryptic cleavage of sarcoplasmic reticulum protein

1974 • 117 citations

Specific interaction of central nervous system myelin basic protein with lipids. Specific regions of the protein sequence protected from the proteolytic action of trypsin

1973 • 108 citations

A study on the influence of the concentration of Mg2+, Pi, K+, Na+, and tris on (Mg2+ + Pi)-supported g-strophanthin binding to (Na+ + K+)-activated ATPase from ox brain

1973 • 106 citations

Effect of ATP on the intermediary steps of the reaction of the (Na++K+)-dependent enzyme system. I. Studied by the use of N-ethylmaleimide inhibition as a tool

1974 • 88 citations

Effect of ATP on the intermediary steps of the reaction of the (Na+ plus K+)-dependent enzyme system. 3. Effect on the p-nitrophenylphosphatase activity of the system.

1974 • 86 citations

Sulfhydryl Groups of Sodium-Potassium Transport Adenosine Triphosphatase

1973 • 80 citations

On the specificity of the ATP-binding site of (Na+ + K+)-activated ATPase from brain microsomes

1971 • 78 citations

Effect of ATP on the intermediary steps of the reaction of the (Na++K+)-dependent enzyme system. III. Effect on the p-nitrophenylphosphatase activity of the system

1974 • 76 citations

Effect of ATP on the intermediary steps of the reaction of the (Na++K+)-dependent enzyme system. II. Effect of a variation in the ATP/Mg2+ ratio

1974 • 68 citations

Substructure of paramyosin. Correlation of helix stability, trypsin digestion kinetics, and amino acid composition

1973 • 44 citations

Ouabain receptor interactions in (Na+ + K+)-ATPase preparations. III. On the stability of the ouabain receptor against physical treatment, hydrolases and SH reagents

1973 • 37 citations

Two Kinds of High Energy Phosphorylated Intermediate, with and without Bound ADP, in the Reaction of Na+-K*-dependent ATPase*

1973 • 36 citations

PURIFICATION OF (Na⁺+ K⁺)-ATPase: ACTIVE SITE DETERMINATIONS AND CRITERIA OF PURITY

1974 • 35 citations

CATION INTERACTIONS WITH DIFFERENT FUNCTIONAL STATES OF THE N<scp>a</scp>⁺, K⁺‐ATP<scp>ase</scp>*

1974 • 33 citations

The effect of proteases on the (Na+ + K+)-activated adenosine triphosphatase system of rat brain

1968 • 30 citations

Effect of trypsin on the proteins of skeletal muscle sarcoplasmic reticulum

1974 • 28 citations

EFFECT OF ATP ON N<scp>a</scp>: K AFFINITY AND CATALYTIC ACTIVITY OF (N<scp>a</scp>⁺+ K⁺)‐ACTIVATED ENZYME SYSTEM

1974 • 14 citations

ANALYSIS OF Na⁺, K⁺AND NUCLEOTIDE INTERACTIONS IN TERMS OF A HETEROTROPIC RELAXATION MODEL FOR (Na⁺-K⁺)-ATPase

1974 • 12 citations

THE USE OF SULFHYDRYL REAGENTS TO IDENTIFY PROTEINS UNDERGOING UGAND-DEPENDENT CONFORMATIONAL CHANGES ASSOCIATED WITH THE FUNCTION OF (NA++ K+)-ATPASE

1974 • 10 citations